ArticlebioRxiv : the preprint server for biology2024
Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility.
Ankit Garg, Silvia Jansen, Rui Zhang, Kory J Lavine, Michael J Greenberg
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 6 citations in OpenAlex.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
5 authors at 2 institutions in 1 country.
Ankit GargDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.
Silvia JansenDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, MO, United States.ORCID 0000-0002-5119-367X Rui ZhangDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.
Kory J LavineCardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-1948-9945 Michael J GreenbergDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-1320-3547 Washington University in St. Louis · USJohns Hopkins University · US
Funding
PRINCIPLES IN CARDIVASCULAR RESEARCH TRAINING PROGRAMT32HL007081 · NHLBI · WASHINGTON UNIVERSITY · PI Abhinav Diwan, Karen Ellen Joynt Maddox · 1985 to 2026
$10.6MSpecification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureR35HL161185 · NHLBI · WASHINGTON UNIVERSITY · PI Kory J. Lavine · 2022 to 2026
$4.3MRegulation of cardiac power output in health and diseaseR01HL141086 · NHLBI · WASHINGTON UNIVERSITY · PI GREENBERG, MICHAEL J · 2018 to 2022
$2.7MThe Role of Donor Innate Immune Responses in Regulating Alloimmunity after Heart TransplantationR01HL151078 · NHLBI · WASHINGTON UNIVERSITY · PI KREISEL, DANIEL, LAVINE, KORY J. · 2020 to 2023
$2.6MStructural and functional studies of axonemal microtubule inner proteins (MIPs)R01GM138854 · NIGMS · WASHINGTON UNIVERSITY · PI ZHANG, RUI · 2020 to 2024
$2.0MRegulation of membrane trafficking by CoroninsR01GM138448 · NIGMS · WASHINGTON UNIVERSITY · PI JANSEN, SILVIA · 2021 to 2025
$1.9MMACROPHAGE HETEROGENEITY IN HEART FAILURE PROGRESSION AND CARDIAC RECOVERYR01HL138466 · NHLBI · WASHINGTON UNIVERSITY · PI LAVINE, KORY J. · 2017 to 2021
$1.9MMACROPHAGE ONTOGENY SHIFTS IN ISCHEMIC HEART DISEASER01HL139714 · NHLBI · WASHINGTON UNIVERSITY · PI LAVINE, KORY J. · 2018 to 2021
$1.5MNHLBI NIH HHS R01 HL138466NHLBI NIH HHS R01 HL139714NHLBI NIH HHS R01 HL141086NHLBI NIH HHS R01 HL151078NHLBI NIH HHS R35 HL161185NHLBI NIH HHS T32 HL007081NIGMS NIH HHS R01 GM138448NIGMS NIH HHS R01 GM138854
6 · The paper itselfAbstract
Skeletal muscle actin (ACTA1) mutations are a prevalent cause of skeletal myopathies consistent with ACTA1's high expression in skeletal muscle. Rare
Indexed as
ActinBiological SciencesBiophysics and Computational Biologycardiomyopathycontractilitymuscle
Identifiers
PMID38559046
PMCPMC10979883
OpenAlexW4392717925
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