Evidence map›Paper›PMID 38559036›Full record

ArticleResearch square2024

Human Coronavirus Infection Reorganizes Spatial Genomic Architecture in Permissive Lung Cells.

Ankush Singhal, Cullen Roth, Sofiya N Micheva-Viteva, Vrinda Venu, Anna Lappala, Jeannie T Lee, Shawn R Starkenburg, Christina R Steadman, Karissa Y Sanbonmatsu

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ankush SinghalTheoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos,NM, USA.
Cullen RothGenomics and Bioanalytics, Los Alamos National Laboratory, Los Alamos, NM, USA.ORCID 0000-0003-4934-6160
Sofiya N Micheva-VitevaBiochemistry and Biotechnology, Los Alamos National Laboratory, Los Alamos, NM, USA.
Vrinda VenuClimate, Ecology & Environment, Los Alamos National Laboratory, Los Alamos, NM, USA.ORCID 0000-0001-6131-3340
Anna LappalaDepartment of Genetics, The Blavatnik Institute, Harvard Medical School, Boston, USA.ORCID 0000-0001-9926-2972
Jeannie T LeeDepartment of Genetics, The Blavatnik Institute, Harvard Medical School, Boston, USA.ORCID 0000-0001-7786-8850
Shawn R StarkenburgGenomics and Bioanalytics, Los Alamos National Laboratory, Los Alamos, NM, USA.
Christina R SteadmanClimate, Ecology & Environment, Los Alamos National Laboratory, Los Alamos, NM, USA.ORCID 0000-0002-9672-5529
Karissa Y SanbonmatsuTheoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos,NM, USA.ORCID 0000-0002-7965-7392
Los Alamos National Laboratory · USBoston University · USHarvard University · US

Funding

Spreading of Xist RNA and Polycomb complexes along the inactive X-chromosome.R01HD097665 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, JEANNIE T · 2019 to 2023
$3.5M
NICHD NIH HHS R01 HD097665
6 · The paper itself

Abstract

Chromatin conformation capture followed by next-generation sequencing in combination with large-scale polymer simulations (4DHiC) produces detailed information on genomic loci interactions, allowing for the interrogation of 3D spatial genomic structures. Here, Hi-C data was acquired from the infection of fetal lung fibroblast (MRC5) cells with

Identifiers

PMID38559036
PMCPMC10980144
OpenAlexW4392757646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.