Evidence map›Paper›PMID 38558219›Full record

ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2024

Identification of key genes and molecular mechanisms of chronic urticaria based on bioinformatics.

Haichao Guo, Lifang Guo, Li Li, Na Li, Xiaoyun Lin, Yanjun Wang

Open access · hybridAbstract read
In one paragraph

Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Comparative efficacy and safety of the treatment by Omalizumab for chronic idiopathic urticaria in the general population: A systematic review and network meta-analysis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Co-regulatory mechanisms and potential markers of oxidative stress-related genes in vitiligo and alopecia areata.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  6. Identification of key genes and molecular mechanisms of chronic urticaria based on bioinformatics.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Haichao GuoDepartment of Acupuncture and Moxibustion, The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Lifang GuoDepartment of Dermatology, Xingtai Hospital of Traditional Chinese Medicine, Xingtai, Hebei, China.
Li LiDepartment of Dermatology, Xingtai Hospital of Traditional Chinese Medicine, Xingtai, Hebei, China.
Na LiDepartment of Psychiatry, The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Xiaoyun LinDepartment of Acupuncture and Moxibustion, The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Yanjun WangDepartment of Acupuncture and Moxibustion, The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Affiliated Hospital of Hebei University · CNXingtai People's Hospital · CNHebei University of Chinese Medicine · CN

Funding

Hebei University of Chinese Medicine 2023 Postgraduate Innovation Funding Project XCXZZBS2023012The General Project of Scientific Research Plan of Hebei Administration of Traditional Chinese Medicine 2022306The General Project of Scientific Research Plan of Hebei Administration of Traditional Chinese Medicine 2023292
6 · The paper itself

Abstract

Chronic urticaria (CU) is characterized by persistent skin hives, redness, and itching, enhanced by immune dysregulation and inflammation. Our main objective is identifying key genes and molecular mechanisms of chronic urticaria based on bioinformatics. We used the Gene Expression Omnibus (GEO) database and retrieved two GEO datasets, GSE57178 and GSE72540. The raw data were extracted, pre-processed, and analyzed using the GEO2R tool to identify the differentially expressed genes (DEGs). The samples were divided into two groups: healthy samples and CU samples. We defined cut-off values of log

Indexed as

Chronic UrticariaGene Expression ProfilingComputational BiologyHumansInflammationQuality of Lifebioinformaticschronic urticariadifferentially expressed genesinflammationmolecular mechanisms

Identifiers

PMID38558219
PMCPMC10982677
OpenAlexW4393383385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.