Evidence map›Paper›PMID 38557382›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2024

[Functional MRI assessment of microstructural and perfusion changes in the kidneys of rats with intrauterine growth restriction].

Can Liang, Ying Li, Xiao-Ri He

Open access · greenAbstract readEnglish Abstract
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Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Can LiangDepartment of Neonatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Ying LiDepartment of Neonatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Xiao-Ri HeDepartment of Neonatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the value of functional magnetic resonance imaging (MRI) techniques, including intravoxel incoherent motion (IVIM), T1 mapping, and T2 mapping, in assessing the microstructural and perfusion changes in the kidneys of rats with intrauterine growth restriction (IUGR).

methodsAn IUGR rat model was established through a low-protein diet during pregnancy. Offspring from pregnant rats on a low-protein diet were randomly divided into an IUGR 8-week group and an IUGR 12-week group, while offspring from pregnant rats on a normal diet were divided into a normal 8-week group and a normal 12-week group (

resultsThe D

conclusionsIVIM MRI can be used to assess and dynamically observe the microstructural and perfusion damage in the kidneys of IUGR rats. MRI T1 mapping can be used to evaluate kidney damage in IUGR rats, and the combination of MRI T1 mapping and T2 mapping can further differentiate renal fibrosis in IUGR rats.

Indexed as

Fetal Growth RetardationKidneyAnimalsCreatinineDiffusion Magnetic Resonance ImagingFemaleMagnetic Resonance ImagingPerfusionPregnancyRatsCreatinineFunctional magnetic resonance imagingIntrauterine growth restrictionIntravoxel incoherent motionKidneyRatT1 mappingT2 mapping

Identifiers

PMID38557382
PMCPMC10986373
OpenAlexW4394742263

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