ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2024
[Specific changes in gut microbiota and short-chain fatty acid levels in infants with cow's milk protein allergy].
Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Association Between Short-Chain Fatty Acids and the Incidence of Food Allergies-Systematic Review.Nutrients · 2025Pooled it
- Microbial metabolites at the nexus of gut-brain communication and neurodevelopmental disorders.Frontiers in nutrition · 2026Review
- [Effect of interleukinZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Severe upper gastrointestinal hemorrhage due to milk protein allergy: A case report.World journal of clinical cases · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the changes in gut microbiota and levels of short-chain fatty acids (SCFA) in infants with cow's milk protein allergy (CMPA), and to clarify their role in CMPA.
methodsA total of 25 infants diagnosed with CMPA at Children's Hospital Affiliated to Zhengzhou University from August 2019 to August 2020 were enrolled as the CMPA group, and 25 healthy infants were selected as the control group. Fecal samples (200 mg) were collected from both groups and subjected to 16S rDNA high-throughput sequencing technology and liquid chromatography-mass spectrometry to analyze the changes in gut microbial composition and metabolites. Microbial diversity was analyzed in conjunction with metabolites.
resultsCompared to the control group, the CMPA group showed altered gut microbial structure and significantly increased α-diversity (
conclusionsCMPA infants have alterations in gut microbial structure, increased microbial diversity, and decreased levels of SCFA, which may contribute to increased intestinal inflammation.
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Registered trials
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