Evidence map›Paper›PMID 38557324›Full record

ArticleBlood transfusion = Trasfusione del sangue2024

Development and evaluation of trigger tools to identify pediatric blood management errors.

Swaminathan Kandaswamy, Cassandra D Josephson, Margo R Rollins, Jennifer Jones, Patricia Zerra, Ruchika Goel, Jennifer Andrews, Jeanne E Hendrickson, Lani Lieberman, Evan W Orenstein

Abstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Swaminathan KandaswamyDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Cassandra D JosephsonDepartments of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Margo R RollinsDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Jennifer JonesCancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, FL, United States of America.
Patricia ZerraAflac Cancer and Blood Disorders Program, Children's Healthcare of Atlanta, Atlanta, GA, United States of America.
Ruchika GoelSimmons Cancer Institute at Southern Illinois University School of Medicine and ImpactLife Blood Centers, Springfield, IL, United States of America.
Jennifer AndrewsDivision of Transfusion Medicine, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Jeanne E HendricksonDepartment of Pathology and Laboratory Medicine, Center for Transfusion and Cellular Therapies, Emory University School of Medicine, Atlanta, GA, United States of America.
Lani LiebermanDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.
Evan W OrensteinDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric Patient Blood Management (PBM) programs require continuous surveillance of errors and near misses. However, most PBM programs rely on passive surveillance methods. Our objective was to develop and evaluate a set of automated trigger tools for active surveillance of pediatric PBM errors. MATERIALS AND

methodsWe used the Rand-UCLA method with an expert panel of pediatric transfusion medicine specialists to identify and prioritize candidate trigger tools for all transfused blood products. We then iteratively developed automated queries of electronic health record (EHR) data for the highest priority triggers. Two physicians manually reviewed a subset of cases meeting trigger tool criteria and estimated each trigger tool's positive predictive value (PPV). We then estimated the rate of PBM errors, whether they reached the patient, and adverse events for each trigger tool across four years in a single pediatric health system.

resultsWe identified 28 potential triggers for pediatric PBM errors and developed 5 automated trigger tools (positive patient identification, missing irradiation, unwashed products despite prior anaphylaxis, transfusion lasting >4 hours, over-transfusion by volume). The PPV for ordering errors ranged from 38-100%. The most frequently detected near miss event reaching patients was first transfusions without positive patient identification (estimate 303, 95% CI: 288-318 per year). The only adverse events detected were from over-transfusions by volume, including 4 adverse events detected on manual review that had not been reported in passive surveillance systems. DISCUSSION: It is feasible to automatically detect pediatric PBM errors using existing data captured in the EHR that enable active surveillance systems. Over-transfusions may be one of the most frequent causes of harm in the pediatric environment.

Indexed as

Medical ErrorsBlood TransfusionChildChild, PreschoolElectronic Health RecordsFemaleHumansInfantMaleTransfusion Reaction

Identifiers

PMID38557324
PMCPMC11576144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.