ArticleCirculation2024
Distinct Plasma Extracellular Vesicle Transcriptomes in Acute Decompensated Heart Failure Subtypes: A Liquid Biopsy Approach.
Open access · greenAbstract readLetter
In one paragraph
Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
What it found
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The trial behind it
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Who cites it
17 citing papers in PubMed, 13 citations in OpenAlex.
- Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circulation research · 2026Review
- Extracellular Vesicles as Mediators of Pathophysiology and Disease Progression in Cardiovascular Diseases.International journal of molecular sciences · 2026Review
- Advancements in extracellular vesicle research.Extracellular vesicle · 2026Article
- Extracellular vesicles in the heart: mediators of intercellular communication in health and disease in vitro.Cell communication and signaling : CCS · 2026Review
- Multi-Organ Physiologic Deficits During Exercise Identify Clinical and Molecular Predisposition to Heart Failure with Preserved Ejection Fraction.Circulation · 2026Article
- Extracellular Vesicles in Cardiac Amyloidosis: From Pathogenesis to Clinical Applications.Diagnostics (Basel, Switzerland) · 2026Review
- A Road Map to Understanding Cardiovascular Disease in Diabetes: From the AHA Strategically Focused Research Network in Cardiometabolic Health and Type 2 Diabetes.Circulation research · 2026Review
- From polygenic risk to digital twins: the future of personalised cardiovascular medicine.Frontiers in cardiovascular medicine · 2026Review
- Review
- Extracellular RNAs in Liquid Biopsy: Applications in MASLD and MASH Diagnosis and Monitoring.Diagnostics (Basel, Switzerland) · 2025Review
- From Natriuretic Peptides to microRNAs: Multi-Analyte Liquid Biopsy Horizons in Heart Failure.Biomolecules · 2025Review
- Histone H2A: a promising diagnostic marker in heart failure with reduced versus preserved ejection fraction.Molecular and cellular biochemistry · 2025Article
- Multi-omics analysis of uterine fluid extracellular vesicles reveals a resemblance with endometrial tissue across the menstrual cycle: biological and translational insights.Human reproduction open · 2025Article
- A perspective from the National Eye Institute Extracellular Vesicle Workshop: Gaps, needs, and opportunities for studies of extracellular vesicles in vision research.Journal of extracellular vesicles · 2024Review
- Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease.medRxiv : the preprint server for health sciences · 2024Article
- The emerging role of extracellular vesicle RNAs as mediators of cardiometabolic diseases: from pathophysiology to clinical applications.Current opinion in physiology · 2024Article
- Role of long noncoding RNAs in diabetes-associated peripheral arterial disease.Cardiovascular diabetology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 2 countries.
Priyanka Gokulnath *Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0003-2813-330X
Michail Spanos *Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0003-1205-4201
H Immo Lehmann *Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0003-4379-283X
Quanhu ShengDepartment of Biostatistics (Q.S.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0001-8951-9295
Rodosthenis RodosthenousInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Finland (R.R.).
Mark ChaffinCardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Cambridge, MA (M.C., P.T.E.).ORCID 0000-0002-1234-5562
Dimitrios VarriasCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0001-9778-1728
Emeli ChatterjeeCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).
Elizabeth HutchinsDivision of Neurogenomics, Translational Genomics Research Institute, Phoenix, AZ (E.H., K.V.K.-J.).ORCID 0000-0003-2543-0798
Guoping LiCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0003-3874-0744
George DaaboulNanoView Biosciences, Boston, MA (G.D.).
Farhan RanaCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).
Ashley Mingyi WangCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).
Kendall Van Keuren-JensenDivision of Neurogenomics, Translational Genomics Research Institute, Phoenix, AZ (E.H., K.V.K.-J.).
Patrick T EllinorCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0002-2067-0533
Ravi Shah *Vanderbilt Translational and Clinical Research Center (R.S.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-4471-7156
Saumya Das *Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (P.G., M.S., H.I.L., D.V., E.C., G.L., F.R., A.M.W., P.T.E., S.D.).ORCID 0000-0002-4521-4606
Massachusetts General Hospital · USBroad Institute · USTranslational Genomics Research Institute · USVanderbilt University Medical Center · USInstitute for Molecular Medicine Finland · FIPrecision BioSciences (United States) · US
Funding
IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6MFunctional role and therapeutic targeting of exosomes and extracellular RNA biomarkers in heart failureR35HL150807 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Saumya Das · 2020 to 2026
$6.7MGenomics of Cardiac ArrhythmiasR01HL139731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2018 to 2022
$3.3MUsing Electrocardiogram Genetics to Inform Arrhythmia RiskR01HL157635 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS, MIRSHAHI, TOORAJ · 2022 to 2025
$2.9MMolecular dissection and imaging of extracellular vesicles to define their origin and targetsUH3TR002878 · NCATS · MASSACHUSETTS GENERAL HOSPITAL · PI DAS, SAUMYA, TALISMAN, TIJANA · 2021 to 2022
$2.2MP.R.I.S.M: Purification of exRNA by Immuno-capture and Sorting using MicrofluidicUH3CA241703 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MATEESCU, BOGDAN, RAFFAI, ROBERT · 2021 to 2022
$1.4MMolecular dissection and imaging of extracellular vesicles to define their origin and targetsUG3TR002878 · NCATS · MASSACHUSETTS GENERAL HOSPITAL · PI DAS, SAUMYA, TALISMAN, TIJANA · 2019 to 2020
$939kNCATS NIH HHS UG3 TR002878NCATS NIH HHS UH3 TR002878NCI NIH HHS UH3 CA241703NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL139731NHLBI NIH HHS R01 HL157635NHLBI NIH HHS R35 HL150807
Abstract
PubMed holds no abstract for this paper.
Indexed as
Extracellular VesiclesHeart FailureHumansLiquid BiopsyTranscriptomecell-free nucleic acidsextracellular vesiclesheart failureheart failure, diastolicheart failure, systolicRNA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.