ArticleScientific reports2024
Genome-wide identification and evolutionary analysis of the AP2/EREBP, COX and LTP genes in Zea mays L. under drought stress.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.
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10 citing papers in PubMed, 12 citations in OpenAlex.
- Genome-wide association study identifies candidate genes for agronomic traits under heat- and combined recurrent drought-and heat-stress in wheat.Scientific reports · 2026Article
- Identification of salt and drought resistance function of maize transcription factor ZmEREB54.BMC plant biology · 2026Article
- Bioinformatic Characterization and Functional Analysis of a Lipid Transfer Protein fromInternational journal of molecular sciences · 2026Article
- Conserved and divergent gene regulatory networks for crop drought resistance.Nature communications · 2026Article
- Genome-wide identification of the P5CS gene family in Psammochloa villosa and functional characterization under drought stress.BMC plant biology · 2026Article
- A machine learning approach to genome-wide association mapping of disease resistance and geographic origin in sorghum.BMC plant biology · 2026Article
- Physiological Responses of Tomato Plants with Varied Susceptibility to Multiple Drought Stress.Antioxidants (Basel, Switzerland) · 2025Article
- Characterization and Role of AP2/EREBP Genes with Decreasing Expression During Leaf Development in 84K Poplar.Plants (Basel, Switzerland) · 2025Article
- GWAS and Meta-QTL Analysis of Kernel Quality-Related Traits in Maize.Plants (Basel, Switzerland) · 2024Article
- Genome-wide association study and genotypic variation for the major tocopherol content in rice grain.Frontiers in plant science · 2024Article
Corrections and comments
- Erratum issued
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2 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
AP2 (APETALA2)/EREBP (ethylene-responsive element-binding protein), cytochrome c oxidase (COX) and nonspecific lipid transfer proteins (LTP) play important roles in the response to drought stress. This is the first study to identify the COX gene in Zea mays L. via genome-wide analysis. The qRT‒PCR results indicated that AP2/EREBP, COX and LTP were downregulated, with fold changes of 0.84, 0.53 and 0.31, respectively, after 12 h of drought stress. Genome-wide analysis identified 78 AP2/EREBP, 6 COX and 10 LTP genes in Z. mays L. Domain analysis confirmed the presence of the AP2 domain, Cyt_c_Oxidase_Vb domain and nsLTP1 in the AP2/EREBP, COX and LTP proteins, respectively. The AP2/EREBP protein family (AP2) includes five different domain types: the AP2/ERF domain, the EREBP-like factor (EREBP), the ethylene responsive factor (ERF), the dehydration responsive element binding protein (DREB) and the SHN SHINE. Synteny analysis of the AP2/EREBP, COX and LTP genes revealed collinearity orthologous relationships in O. sativa, H. vulgare and A. thaliana. AP2/EREBP genes were found on the 10 chromosomes of Z. mays L. COX genes were found on chromosomes 1, 3, 4, 5, 7 and 8. LTP genes were found on chromosomes 1, 3, 6, 8, 9 and 10. In the present study, the Ka/Ks ratios of the AP2/EREBP paralogous pairs indicated that the AP2/EREBP genes were influenced primarily by purifying selection, which indicated that the AP2/EREBP genes received strong environmental pressure during evolution. The Ka/Ks ratios of the COX-3/COX-4 paralogous pairs indicate that the COX-3/COX-4 genes were influenced primarily by Darwinian selection (driving change). For the LTP genes, the Ka/Ks ratios of the LTP-1/LTP-10, LTP-5/LTP-3 and LTP-4/LTP-8 paralogous pairs indicate that these genes were influenced primarily by purifying selection, while the Ka/Ks ratios of the LTP-2/LTP-6 paralogous pairs indicate that these genes were influenced primarily by Darwinian selection. The duplication time of the AP2/EREBP paralogous gene pairs in Z. mays L. ranged from approximately 9.364 to 100.935 Mya. The duplication time of the COX-3/COX-4 paralogous gene pair was approximately 5.217 Mya. The duplication time of the LTP paralogous gene pairs ranged from approximately 19.064 to 96.477 Mya. The major focus of research is to identify the genes that are responsible for drought stress tolerance to improve maize for drought stress tolerance. The results of the present study will improve the understanding of the functions of the AP2/EREBP, COX and LTP genes in response to drought stress.
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