Evidence map›Paper›PMID 38555551›Full record

ArticleArchives of microbiology2024

Isolation and characterization of a relatively broad-spectrum phage against Escherichia coli.

Haiyan Zhang, Xiapei Hu, Zhengxing Ma, Xiangkuan Zhen, Panpan Tong, Guangxi Zhai, Shuang Zhang, Wei Zhang

Abstract read
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In one paragraph

Article in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haiyan Zhang *Department of Food and Biology Engineering, Wuhu Institute of Technology, Wuhu, 241003, China.
Xiapei Hu *College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Zhengxing MaDepartment of Food and Biology Engineering, Wuhu Institute of Technology, Wuhu, 241003, China.
Xiangkuan ZhenCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Panpan TongCollege of Animal Medical, Xinjiang Uygur Autonomous Region, Xinjiang Agricultural University, Urumqi, 830052, China.
Guangxi ZhaiWuhu Qingshui White Meat Wholesale Market Co., LTD, Wuhu, 241000, China.
Shuang ZhangDepartment of Food and Biology Engineering, Wuhu Institute of Technology, Wuhu, 241003, China. goodluck_zs@163.com.
Wei ZhangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China. vszw@njau.edu.cn.

Funding

Natural Science Foundation of Anhui Province 2022AH052192Natural Science Research Project of Anhui Province KJ2021ZD0153University-Level Science and Technology Team of Wuhu Institute of Technology wzykjtd202002
6 · The paper itself

Abstract

Multiple pathogenic types or serotypes restrict treatment for colibacillosis. In addition, rising antibiotic resistance has heightened public awareness to prevent and control pathogenic Escherichia coli. The bacteriophage is a viable technique to treat colibacillosis as an alternative to antibiotics. In this study, PH444, a relatively broad-spectrum obligate lytic phage, was screened from 48 Shiga toxin-producing Escherichia coli (STEC) phages isolated from farm manure samples and sewage samples in order to conduct genome-wide analysis, biological characterization, and a bacterial challenge experiment in milk. The results demonstrated that PH444 was a T7-like phage with a double-stranded DNA of 115,111 bp that belongs to the Kuravirus and was stable at temperatures between 4 and 50 °C and a pH range of 3 to 11. After adding PH444, the bacterial load in milk could be reduced from 3 × 10

Indexed as

BacteriophagesEscherichia coli InfectionsPodoviridaeAnti-Bacterial AgentsEscherichia coliHumansAnti-Bacterial AgentsKuravirusPhagePhage biocontrolShiga toxin-producing Escherichia coli

Identifiers

PMID38555551

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.