Evidence map›Paper›PMID 38555533›Full record

ArticleAging2024

Inflammatory risk of albumin combined with C-reactive protein predicts long-term cardiovascular risk in patients with diabetes.

Xiaoqun Xu, Houyong Zhu, Hanxin Wang, Xinyu Zhu, Libin Liu, Fengwei Zhang, Hongjuan Zhou, Mingzhi Zhu, Lingshan Dai, Long Cai

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xiaoqun XuCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Houyong ZhuDepartment of Cardiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Hanxin WangThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Xinyu ZhuZhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Libin LiuCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Fengwei ZhangCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Hongjuan ZhouCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Mingzhi ZhuCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Lingshan DaiCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Long CaiCentre of Laboratory Medicine, Hangzhou Red Cross Hospital, Zhejiang, China.
Hangzhou Red Cross Hospital · CNZhejiang Chinese Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe purpose of this study was to evaluate the predictive value of inflammatory risk as defined by the Glasgow Prognostic Score (GPS) for cardiovascular death in patients with diabetes.

methodsThis study included 4956 patients (≥18 years old) with diabetes in the National Health and Nutrition Survey from 1999 to 2010. The mortality rate was determined by the correlation with the national death index on December 31, 2019. The GPS was composed of the serum C-reactive protein and the albumin. The primary outcome was cardiovascular death and the secondary outcome was all-cause death. The Cox proportional risk model adjusted for demographic factors and traditional cardiovascular risk factors was used to analyze the cumulative risk of outcomes.

resultsAmong 4956 diabetes patients with a median follow-up of 10.9 years, 601 cardiovascular deaths and 2187 all-cause deaths were recorded. After adequate model adjustment, compared with the low GPS group, the high GPS group (HR, 1.257 (1.007-1.570),

conclusionsThe inflammatory risk as defined by the GPS was closely related to the increased risk of cardiovascular and all-cause death in patients with diabetes. It may be a convenient and efficient clinical practical risk assessment tool for patients with diabetes.

Indexed as

Cardiovascular DiseasesC-Reactive ProteinAdultAgedBiomarkersDiabetes MellitusFemaleHeart Disease Risk FactorsHumansInflammationMaleMiddle AgedNutrition SurveysPrognosisRisk AssessmentRisk FactorsBiomarkersC-Reactive ProteinSerum Albuminalbumincardiovascular deathC-reactive proteindiabetesglasgow prognostic score

Identifiers

PMID38555533
PMCPMC11042957
OpenAlexW4393319203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.