Evidence map›Paper›PMID 38555278›Full record

ArticleOncogene2024

ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases.

Yu Dong, Keshu Hu, Jiayu Zhang, Mengxuan Zhu, Mengling Liu, Yitao Yuan, Xun Sun, Zhenghang Xu, Suyao Li, Yanjing Zhu and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Oncogene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Review
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  11. Review
  12. The role ofFrontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yu Dong *Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Keshu Hu *Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Jiayu Zhang *Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Mengxuan Zhu *Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Mengling LiuDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yitao YuanDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Xun SunDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhenghang XuDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Suyao LiDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yanjing ZhuDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Chi ZhangDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Pengfei ZhangDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. zhang.pengfei@zs-hospital.sh.cn.
Tianshu LiuDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. liutianshu1969@126.com.ORCID 0000-0002-2318-2869
Sun Yat-sen University · CNShanghai Medical College of Fudan University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81802370
6 · The paper itself

Abstract

Gastric carcinoma (GC) is regarded as one of the deadliest cancer characterized by diversity and haste metastasis and suffers limited understanding of the spatial variation between primary and metastatic GC tumors. In this project, transcriptome analysis on 46 primary tumorous, adjacent non-tumorous, and metastatic GC tissues was performed. The results demonstrated that metastatic tumorous tissues had diminished CD8

Indexed as

Stomach NeoplasmsTumor MicroenvironmentCD8-Positive T-LymphocytesFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMacrophagesMaleMiddle AgedNeoplasm MetastasisPrognosisRNA-SeqSingle-Cell Gene Expression Analysis

Identifiers

PMID38555278
OpenAlexW4393336899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.