ArticleNeuroImage2024
In vivo mapping of hippocampal venous vasculature and oxygenation using susceptibility imaging at 7T.
Article in NeuroImage, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Large-Vessel Venous Signal Confounds Apparent Amygdala Activation in BOLD fMRI.bioRxiv : the preprint server for biology · 2026Article
- A Mechanistic Model of Brain Necrosis Progression Based on Vascular Heterogeneity.International journal of radiation oncology, biology, physics · 2026Article
- Hippocampal subfields in aging: Sex-specific trajectories in structure and hemodynamics.NeuroImage · 2025Article
- Resting-State Activity Changes Induced by tDCS in MS Patients and Healthy Controls: A Simultaneous tDCS rs-fMRI Study.Bioengineering (Basel, Switzerland) · 2025Article
- Imaging arterial and venous vessels using Iron Dextran enhanced multi-echo 3D gradient echo MRI at 7T.NMR in biomedicine · 2024Article
- The impact of body position on neurofluid dynamics: present insights and advancements in imaging.Frontiers in aging neuroscience · 2024Review
- Automated brain segmentation and volumetry in dementia diagnostics: a narrative review with emphasis on FreeSurfer.Frontiers in aging neuroscience · 2024Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Mapping the small venous vasculature of the hippocampus in vivo is crucial for understanding how functional changes of hippocampus evolve with age. Oxygen utilization in the hippocampus could serve as a sensitive biomarker for early degenerative changes, surpassing hippocampal tissue atrophy as the main source of information regarding tissue degeneration. Using an ultrahigh field (7T) susceptibility-weighted imaging (SWI) sequence, it is possible to capture oxygen-level dependent contrast of submillimeter-sized vessels. Moreover, the quantitative susceptibility mapping (QSM) results derived from SWI data allow for the simultaneous estimation of venous oxygenation levels, thereby enhancing the understanding of hippocampal function. In this study, we proposed two potential imaging markers in a cohort of 19 healthy volunteers aged between 20 and 74 years. These markers were: 1) hippocampal venous density on SWI images and 2) venous susceptibility (Δχ
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.