Evidence map›Paper›PMID 38554545›Full record

ArticleThe Journal of surgical research2024

Association of Race and Ethnicity With Postoperative Gabapentinoid and Opioid Prescribing Trends for Older Adults.

Tasce Bongiovanni, Siqi Gan, Emily Finlayson, Joseph S Ross, James D Harrison, W John Boscardin, Michael A Steinman

Abstract read
In one paragraph

Article in The Journal of surgical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tasce BongiovanniDepartment of Surgery, University of California San Francisco School of Medicine, San Francisco, California. Electronic address: tasce.bongiovanni@ucsf.edu.
Siqi GanDivision of Geriatrics, University of California San Francisco School of Medicine, San Francisco, California; Northern California Institute for Research and Education, San Francisco, California.
Emily FinlaysonDepartment of Surgery, University of California San Francisco School of Medicine, San Francisco, California.
Joseph S RossCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut; Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; Department of Health Policy and Management, Yale University School of Public Health, New Haven, Connecticut.
James D HarrisonDivision of Hospital Medicine, University of California San Francisco School of Medicine, San Francisco, California.
W John BoscardinDepartment of Medicine, University of California San Francisco School of Medicine, San Francisco, California; Department of Epidemiology & Biostatistics, University of California San Francisco School of Medicine, San Francisco, California.
Michael A SteinmanDivision of Geriatrics, University of California San Francisco School of Medicine, San Francisco, California; San Francisco VA Medical Center, San Francisco, California.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale-Mayo FDA Center for Excellence in Regulatory Science and InnovationU01FD005938 · FDA · YALE UNIVERSITY · PI Joseph Solomon Ross · 2016 to 2026
$25.4M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Unnecessary and Harmful Medication Use in Older Adults with DementiaP01AG066605 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI R. Sean Morrison · 2020 to 2026
$17.7M
U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
Understanding and Improving Surgical Decision-Making for Persons Living with Dementia, their Family Caregivers, and their Providers: A Mixed Methods StudyR01AG067507 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISSMAN, JOEL S. · 2020 to 2024
$4.4M
Understanding hospital value: provider, hospital and community effectsR01HS022882 · AHRQ · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HORWITZ, LEORA · 2014 to 2023
$2.9M
Prescribing cascades in older adults with and without dementiaK24AG049057 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEINMAN, MICHAEL A. · 2015 to 2025
$1.8M
Optimizing surgical decision-making for nursing home residents undergoing surgery for bladder and bowel dysfunctionR01AG058616 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SUSKIND, ANNE M. · 2018 to 2021
$1.7M
Leveraging Physician Networks to Improve Care and Outcomes for Low-Income PopulationsR01HL144644 · NHLBI · YALE UNIVERSITY · PI NDUMELE, CHIMA · 2019 to 2021
$1.6M
Medical reversals: De-implementing ineffective and unsafe treatmentsR01HS025164 · AHRQ · UNIVERSITY OF MINNESOTA · PI KARACA-MANDIC, PINAR · 2017 to 2020
$1.4M
AHRQ HHS R01 HS022882AHRQ HHS R01 HS025164FDA HHS U01 FD005938NCATS NIH HHS KL2 TR001870NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL144644NIA NIH HHS K01 AG073533NIA NIH HHS K23 AG073523NIA NIH HHS K24 AG049057NIA NIH HHS P01 AG066605NIA NIH HHS P30 AG044281NIA NIH HHS R01 AG058616NIA NIH HHS R01 AG067507NIA NIH HHS R24 AG064025
6 · The paper itself

Abstract

backgroundDisparities in opioid prescribing by race/ethnicity have been described in many healthcare settings, with White patients being more likely to receive an opioid prescription than other races studied. As surgeons increase prescribing of nonopioid medications in response to the opioid epidemic, it is unknown whether postoperative prescribing disparities also exist for these medications, specifically gabapentinoids.

methodsWe conducted a retrospective cohort study using a 20% Medicare sample for 2013-2018. We included patients ≥66 years without prior gabapentinoid use who underwent one of 14 common surgical procedures. The primary outcome was the proportion of patients prescribed gabapentinoids at discharge among racial and ethnic groups. Secondary outcomes were days' supply of gabapentinoids, opioid prescribing at discharge, and oral morphine equivalent (OME) of opioid prescriptions. Trends over time were constructed by analyzing proportion of postoperative prescribing of gabapentinoids and opioids for each year. For trends by year by racial/ethnic groups, we ran a multivariable logistic regression with an interaction term of procedure year and racial/ethnic group.

resultsOf the 494,922 patients in the cohort (54% female, 86% White, 5% Black, 5% Hispanic, mean age 73.7 years), 3.7% received a new gabapentinoid prescription. Gabapentinoid prescribing increased over time for all groups and did not differ significantly among groups (P = 0.13). Opioid prescribing also increased, with higher proportion of prescribing to White patients than to Black and Hispanic patients in every year except 2014.

conclusionsWe found no significant prescribing variation of gabapentinoids in the postoperative period between racial/ethnic groups. Importantly, we found that despite national attention to disparities in opioid prescribing, variation continues to persist in postoperative opioid prescribing, with a higher proportion of White patients being prescribed opioids, a difference that persisted over time.

Indexed as

Analgesics, OpioidDrug PrescriptionsGabapentinPostoperative PainPractice Patterns, Physicians'AgedAged, 80 and overBlack or African AmericanEthnicityFemaleHealthcare DisparitiesHispanic or LatinoHumansMaleMedicareRetrospective StudiesAnalgesics, OpioidGabapentinDisparitiesGabapentinoidsOlder adultsOpioidsPostoperative painRace

Identifiers

PMID38554545
PMCPMC11630109

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.