Evidence map›Paper›PMID 38554078›Full record

ArticleACS applied materials & interfaces2024

Injectable Phage-Loaded Microparticles Effectively Release Phages to Kill Methicillin-Resistant

Yajing Xu, Tao Yang, Yao Miao, Qinglei Zhang, Mingying Yang, Chuanbin Mao

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  7. Advances in nanotechnology for the therapy of bacterial pneumonia.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yajing XuSchool of Materials Science and Engineering, Zhejiang University, Hangzhou 310058, Zhejiang, China.
Tao YangSchool of Materials Science and Engineering, Zhejiang University, Hangzhou 310058, Zhejiang, China.
Yao MiaoSchool of Materials Science and Engineering, Zhejiang University, Hangzhou 310058, Zhejiang, China.
Qinglei ZhangInstitute of Applied Bioresource Research, College of Animal Science, Zhejiang University, Yuhangtang Road 866, Hangzhou 310058, Zhejiang, China.
Mingying YangInstitute of Applied Bioresource Research, College of Animal Science, Zhejiang University, Yuhangtang Road 866, Hangzhou 310058, Zhejiang, China.ORCID 0000-0003-1256-6514
Chuanbin MaoDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin 999077, Hong Kong SAR, China.ORCID 0000-0002-8142-3659
Zhejiang University · CNChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of bacterial multidrug antibiotic resistance has led to a serious threat to public health, emphasizing the urgent need for alternative antibacterial therapeutics. Lytic phages, a class of viruses that selectively infect and kill bacteria, offer promising potential as alternatives to antibiotics. However, injectable carriers with a desired release profile remain to be developed to deliver them to infection sites. To address this challenge, phage-loaded microparticles (Phage-MPs) have been developed to deliver phages to the infection site and release phages for an optimal therapeutic effect. The Phage-MPs are synthesized by allowing phages to be electrostatically attached onto the porous polyethylenimine-modified silk fibroin microparticles (SF-MPs). The high specific surface area of SF-MPs allows them to efficiently load phages, reaching about 1.25 × 10

Indexed as

BacteriophagesMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsMiceStaphylococcus PhagesTissue DistributionAnti-Bacterial Agentsabdominal infectionantibacterial agentsbacteriophagedrug-resistancemicroparticle

Identifiers

PMID38554078
PMCPMC11009905
OpenAlexW4393345641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.