Evidence map›Paper›PMID 38553647›Full record

ArticleEuropean child & adolescent psychiatry2024

Positive psychotic symptoms as a marker of clinical severity in a transdiagnostic sample of help-seeking adolescents.

Janko M Kaeser, Stefan Lerch, Silvano Sele, Corinna Reichl, Julian Koenig, Ines Mürner-Lavanchy, Thomas Berger, Michael Kaess, Marialuisa Cavelti

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In one paragraph

Article in European child & adolescent psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Janko M KaeserUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland.
Stefan LerchUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland.
Silvano SeleUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland.
Corinna ReichlUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland.
Julian KoenigDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Ines Mürner-LavanchyUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland.
Thomas BergerDepartment of Clinical Psychology and Psychotherapy, University of Bern, Bern, Switzerland.
Michael KaessUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland.
Marialuisa CaveltiUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse, 111, 3000, Bern, Switzerland. marialuisa.cavelti@unibe.ch.ORCID http://orcid.org/0000-0003-4726-396X
University of Bern · CHUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to examine the association between the presence, number, and type of positive psychotic symptoms (PPS) and clinical severity in adolescent patients. Five hundred-six patients aged 11-17 years were assigned to either the noPPS (n = 341), the delusional beliefs only (del; n = 32), the hallucinations only (hall; n = 80), or the delusional beliefs and hallucinations (del&hall; n = 53) group. Generalized Structural Equation Modeling was applied to identify the best-fitting model representing clinical severity indicated by psychiatric diagnoses, depressivity, personality pathology, non-suicidal self-injury, suicide attempts, perceived stress, and psychosocial impairments, assessed by interviews and questionnaires. The groups were compared concerning the final model's factors. The final model consisted of three factors representing psychopathology and functional impairments, self-harming behavior, and perceived stress (BIC difference to reference model: 103.99). Participants with any PPS scored higher on all factors than the noPPS group (differences in SD: 0.49-1.48). Additionally, the del&hall group scored 1.31 SD higher on psychopathology and functional impairments than the hall group, and 1.16 SD higher on self-harming behavior compared to the del group. Finally, the hall group scored 0.84 SD higher on self-harming behavior than the del group, with no group differences in the other factors. In adolescent patients, the presence of PPS may represent a marker for a more severe form of mental disorder, with hallucinations being indicative of self-harming behavior. Early transdiagnostic assessment of PPS seems indicated as it may inform treatment in the context of clinical staging.

Indexed as

DelusionsHallucinationsPsychotic DisordersAdolescentChildFemaleHumansMalePsychiatric Status Rating ScalesSeverity of Illness IndexAdolescenceDimensionalPsychosisTransdiagnosticYouth

Identifiers

PMID38553647
PMCPMC11564335
OpenAlexW4393344482

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.