Evidence map›Paper›PMID 38553601›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Association of low hemoglobin at birth and neurodevelopmental outcomes in preterm neonates ≤28 weeks' gestation: a retrospective cohort study.

Mohamed Elkhouli, Kamini Raghuram, Thanna Elhanafy, Elizabeth Asztalos, Rudaina Banihani, Prakesh S Shah, Adel Mohamed

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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mohamed ElkhouliDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-7531-8641
Kamini RaghuramDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Thanna ElhanafyDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Elizabeth AsztalosDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Rudaina BanihaniDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Prakesh S ShahDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Adel MohamedDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada. Adel.mohamed@sinaihealth.ca.ORCID 0000-0001-8031-6627
University of Toronto · CASunnybrook Health Science Centre · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare neurodevelopmental outcomes at 18-24 months corrected age (CA) for preterm infants who had hemoglobin levels <120 g/l versus those with hemoglobin level ≥120 g/l at birth.

methodsWe included infants of ≤28 weeks gestational age (GA) born between January 2009 and June 2018. The primary outcome was neurodevelopmental impairment (NDI) at 18-24 months. Multivariable logistic regression was applied to determine the association.

resultsOf the 2351 eligible neonates, 351 (14.9%) had hemoglobin levels <120 g/L at birth. Of the 2113 surviving infants, 1534 (72.5%) underwent developmental follow-up at 18-24 months CA. There was no statistically significant difference in ND outcomes between the two groups. The composite outcome of death or NDI was significantly higher in the low hemoglobin group.

conclusionIn preterm infants ≤28 weeks GA, initial hemoglobin <120 g/L at birth was not associated with neurodevelopmental impairment at 18-24 months CA among survivors.

Indexed as

Gestational AgeHemoglobinsInfant, PrematureNeurodevelopmental DisordersFemaleHumansInfantInfant, NewbornLogistic ModelsMaleRetrospective StudiesHemoglobins

Identifiers

PMID38553601
OpenAlexW4393318298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.