ArticleScientific reports2024
Blood urea nitrogen to serum albumin ratio: a novel mortality indicator in intensive care unit patients with coronary heart disease.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 25 citations in OpenAlex.
- Association between the blood urea nitrogen to albumin ratio and all-cause mortality in critically ill patients with liver cirrhosis.BMC gastroenterology · 2026Article
- Development and validation of a prognostic model incorporating the blood urea nitrogen-to-albumin ratio for predicting mortality in methicillin-resistant Staphylococcus aureus bloodstream infection.BMC infectious diseases · 2026Article
- Association Between the Ratio of Blood Urea Nitrogen to Serum Albumin, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease Risk in USA Adults: An Observational Cohort Analysis.Health science reports · 2026Article
- Blood urea nitrogen-to-albumin ratio predicts mortality in dogs with pyometra.Journal of veterinary science · 2026Article
- Elevated blood urea nitrogen-to-albumin ratio is associated with incident sepsis-associated delirium: evidence from a weighted competing-risk analysis in a multicenter cohort study.Frontiers in nutrition · 2026Article
- Increased blood urea nitrogen to serum albumin ratio is associated with poor prognosis in patients with acute pancreatitis: a retrospective cohort study.Archives of medical science : AMS · 2026Article
- Bridging the gap between biomarkers and bedside decisions: the prognostic value of the blood urea nitrogen-to-albumin ratio in sepsis-associated AKI.Frontiers in nutrition · 2026Article
- Blood urea nitrogen to albumin ratio as a robust predictor of in-hospital mortality in patients with predicted severe acute pancreatitis: a retrospective multicenter observational study.International journal of surgery (London, England) · 2026Observational
- BUN-albumin ratio as a prognostic marker in decompensated heart failure with reduced ejection fraction.American heart journal plus : cardiology research and practice · 2026Article
- Association of the blood urea nitrogen to serum albumin ratio on prognosis in patients with bacterial meningitis: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Article
- The association between blood urea nitrogen to albumin ratio and 28-day ICU mortality in sepsis patients: a retrospective cohort study.European journal of medical research · 2025Article
- Association of Plasma Osmolality with Cardiovascular Disease Risk: Evidence from the National Health and Nutrition Examination Survey Database.Arquivos brasileiros de cardiologia · 2025Article
- Association between the blood urea nitrogen to serum albumin ratio and the risk of mortality in patients with chronic kidney disease: a cohort study.BMC nephrology · 2025Article
- Association of blood urea nitrogen to albumin ratio with mortality in acute pancreatitis.Scientific reports · 2025Article
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- Alkaline Phosphatase to Albumin Ratio as a Novel Predictor of All-Cause Mortality in Critically Ill Patients With Atrial Fibrillation.Cardiology research and practice · 2025Article
- Constructing a Predictive Model to Evaluate the Risk of CHD Based on New Metabolic Indicators.Vascular health and risk management · 2025Article
- The association between blood urea nitrogen to serum albumin ratio and 28 day in-hospital mortality in patients with chronic heart failure and sepsis: a pilot retrospective study.Frontiers in cardiovascular medicine · 2025Article
- Exploring the value of blood urea nitrogen-to-albumin ratio in patients with acute pancreatitis admitted to the intensive care unit: a retrospective cohort study.Frontiers in nutrition · 2025Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The blood urea nitrogen to albumin ratio (BAR) has been demonstrated as a prognostic factor in sepsis and respiratory diseases, yet its role in severe coronary heart disease (CHD) remains unexplored. This retrospective study, utilizing data from the Medical Information Mart for Intensive Care-IV database, included 4254 CHD patients, predominantly male (63.54%), with a median age of 74 years (IQR 64-83). Primary outcomes included in-hospital, 28-day and 1-year all-cause mortality after ICU admission. The Kaplan-Meier curves, Cox regression analysis, multivariable restricted cubic spline regression were employed to assess association between BAR index and mortality. In-hospital, within 28-day and 1-year mortality rates were 16.93%, 20.76% and 38.11%, respectively. Multivariable Cox proportional hazards analysis revealed associations between the increased BAR index and higher in-hospital mortality (HR 1.11, 95% CI 1.02-1.21), 28-day mortality (HR 1.17, 95% CI 1.08-1.27) and 1-year mortality (HR 1.23, 95% CI 1.16-1.31). Non-linear relationships were observed for 28-day and 1-year mortality with increasing BAR index (both P for non-linearity < 0.05). Elevated BAR index was a predictor for mortality in ICU patients with CHD, offering potential value for early high-risk patient identification and proactive management by clinicians.
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