Evidence map›Paper›PMID 38553447›Full record

ArticleNature communications2024

Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice.

Zsofia Hevesi, Joanne Bakker, Evgenii O Tretiakov, Csaba Adori, Anika Raabgrund, Swapnali S Barde, Martino Caramia, Thomas Krausgruber, Sabrina Ladstätter, Christoph Bock and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Neuropeptides: The Evergreen Jack-of-All-Trades in Neuronal Circuit Development and Regulation.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Zsofia Hevesi *Department of Molecular Neurosciences, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Joanne Bakker *Department of Neuroscience, Biomedicum 7D, Karolinska Institutet, Solna, Sweden.
Evgenii O TretiakovDepartment of Molecular Neurosciences, Center for Brain Research, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0001-5920-2190
Csaba AdoriDepartment of Neuroscience, Biomedicum 7D, Karolinska Institutet, Solna, Sweden.
Anika RaabgrundDepartment of Molecular Neurosciences, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Swapnali S BardeDepartment of Neuroscience, Biomedicum 7D, Karolinska Institutet, Solna, Sweden.
Martino CaramiaDepartment of Neuroscience, Biomedicum 7D, Karolinska Institutet, Solna, Sweden.
Thomas KrausgruberCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.ORCID http://orcid.org/0000-0002-1374-0329
Sabrina LadstätterCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Christoph BockCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.ORCID http://orcid.org/0000-0001-6091-3088
Tomas HökfeltDepartment of Neuroscience, Biomedicum 7D, Karolinska Institutet, Solna, Sweden. Tomas.Hokfelt@ki.se.ORCID http://orcid.org/0000-0002-3587-0116
Tibor HarkanyDepartment of Molecular Neurosciences, Center for Brain Research, Medical University of Vienna, Vienna, Austria. Tibor.Harkany@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-6637-5900
Karolinska Institutet · SEAustrian Academy of Sciences · ATMedical University of Vienna · AT

Funding

Austrian Science Fund FWF DOC 33EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013)) 2020-AdG-101021016Novo Nordisk Fonden (Novo Nordisk Foundation) NNF23OC0084476Vetenskapsrådet (Swedish Research Council) 2023-03058
6 · The paper itself

Abstract

The significance of transient neuropeptide expression during postnatal brain development is unknown. Here, we show that galanin expression in the ventrobasal thalamus of infant mice coincides with whisker map development and modulates subcortical circuit wiring. Time-resolved neuroanatomy and single-nucleus RNA-seq identified complementary galanin (Gal) and galanin receptor 1 (Galr1) expression in the ventrobasal thalamus and the principal sensory nucleus of the trigeminal nerve (Pr5), respectively. Somatodendritic galanin release from the ventrobasal thalamus was time-locked to the first postnatal week, when Gal

Indexed as

GalaninVibrissaeAnimalsAxonsBrainHumansMiceThalamusGalaningalanin protein, mouse

Identifiers

PMID38553447
PMCPMC10980825
OpenAlexW4393304975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.