Evidence map›Paper›PMID 38552414›Full record

ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2024

Cortical and white matter substrates supporting visuospatial working memory.

Riyo Ueda, Kazuki Sakakura, Takumi Mitsuhashi, Masaki Sonoda, Ethan Firestone, Naoto Kuroda, Yu Kitazawa, Hiroshi Uda, Aimee F Luat, Elizabeth L Johnson and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  6. Visualization of functional and effective connectivity underlying auditory descriptive naming.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Riyo UedaDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; National Center Hospital, National Center of Neurology and Psychiatry, Tokyo 1878551, Japan. Electronic address: hj9794@wayne.edu.
Kazuki SakakuraDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois 60612, USA; Department of Neurosurgery, University of Tsukuba, Tsukuba 3058575, Japan. Electronic address: Kazuki_Sakakura@rush.edu.
Takumi MitsuhashiDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurosurgery, Juntendo University, School of Medicine, Tokyo 1138421, Japan. Electronic address: tmituha@juntendo.ac.jp.
Masaki SonodaDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurosurgery, Yokohama City University, Yokohama 2360004, Japan. Electronic address: sonoda.mas.pu@yokohama-cu.ac.jp.
Ethan FirestoneDepartment of Physiology, Wayne State University, Detroit, Michigan 48202, USA. Electronic address: efirest@med.wayne.edu.
Naoto KurodaDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan. Electronic address: naoto.kuroda@wayne.edu.
Yu KitazawaDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurology and Stroke Medicine, Yokohama City University, Yokohama 2360004, Japan. Electronic address: yu_kitazawa@wayne.edu.
Hiroshi UdaDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurosurgery, Osaka Metropolitan University Graduate School of Medicine, Osaka 5458585, Japan. Electronic address: hm9480@wayne.edu.
Aimee F LuatDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurology, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Pediatrics, Central Michigan University, Mt. Pleasant, Michigan 48858, USA. Electronic address: aluat@dmc.org.
Elizabeth L JohnsonDepartments of Medical Social Sciences, Pediatrics, and Psychology, Northwestern University, Chicago, Illinois 60611, USA. Electronic address: eljohnson@northwestern.edu.
Noa OfenLife-Span Cognitive Neuroscience Program, Institute of Gerontology and Merrill Palmer Skillman Institute, Wayne State University, Detroit, Michigan 48202, USA; Department of Psychology, Wayne State University, Detroit, Michigan 48202, USA. Electronic address: noa.ofen@wayne.edu.
Eishi AsanoDepartment of Pediatrics, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Department of Neurology, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA; Translational Neuroscience Program, Wayne State University, Detroit, Michigan 48201, USA. Electronic address: easano@med.wayne.edu.
Wayne State University · USCentral Michigan University · USNorthwestern University · USRush University Medical Center · US

Funding

Functional brain mapping in pediatric neurosurgeryR01NS064033 · NINDS · WAYNE STATE UNIVERSITY · PI EISHI ASANO · 2009 to 2026
$5.7M
DEVELOPMENT OF MEMORY NETWORKS IN CHILDRENR01MH107512 · NIMH · WAYNE STATE UNIVERSITY · PI Noa Ofen · 2016 to 2026
$5.0M
Measuring Electrical Activity from the Human Brain to Predict Memory Formation and Behavior Across the LifespanR00NS115918 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JOHNSON, ELIZABETH · 2022 to 2024
$843k
Measuring Electrical Activity from the Human Brain to Predict Memory Formation and Behavior Across the LifespanK99NS115918 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JOHNSON, ELIZABETH · 2020 to 2021
$258k
NIMH NIH HHS R01 MH107512NINDS NIH HHS K99 NS115918NINDS NIH HHS R00 NS115918NINDS NIH HHS R01 NS064033
6 · The paper itself

Abstract

objectiveIn tasks involving new visuospatial information, we rely on working memory, supported by a distributed brain network. We investigated the dynamic interplay between brain regions, including cortical and white matter structures, to understand how neural interactions change with different memory loads and trials, and their subsequent impact on working memory performance.

methodsPatients undertook a task of immediate spatial recall during intracranial EEG monitoring. We charted the dynamics of cortical high-gamma activity and associated functional connectivity modulations in white matter tracts.

resultsElevated memory loads were linked to enhanced functional connectivity via occipital longitudinal tracts, yet decreased through arcuate, uncinate, and superior-longitudinal fasciculi. As task familiarity grew, there was increased high-gamma activity in the posterior inferior-frontal gyrus (pIFG) and diminished functional connectivity across a network encompassing frontal, parietal, and temporal lobes. Early pIFG high-gamma activity was predictive of successful recall. Including this metric in a logistic regression model yielded an accuracy of 0.76.

conclusionsOptimizing visuospatial working memory through practice is tied to early pIFG activation and decreased dependence on irrelevant neural pathways. SIGNIFICANCE: This study expands our knowledge of human adaptation for visuospatial working memory, showing the spatiotemporal dynamics of cortical network modulations through white matter tracts.

Indexed as

Cerebral CortexMemory, Short-TermWhite MatterAdultFemaleHumansMaleMiddle AgedSpace PerceptionVisual PerceptionYoung AdultBroadband high-frequency activityFunctional brain mappingIntracranial EEG recordingPediatric epilepsy surgeryPhysiological high-frequency oscillations (HFOs)

Identifiers

PMID38552414
PMCPMC11102300
OpenAlexW4392921813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.