Evidence map›Paper›PMID 38552323›Full record

ArticleJNCI cancer spectrum2024

Financial-legal navigation reduces financial toxicity of pediatric, adolescent, and young adult cancers.

Jean Edward, Kimberly D Northrip, Mary Kay Rayens, Andrea Welker, Rachel O'Farrell, Jennifer Knuf, Haafsah Fariduddin, Julia Costich, John D'Orazio

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JNCI cancer spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05876325 (Leveraging Medical Legal Partnerships to Enhance Patient-Centered, Team-Based Cost Conversations With Pediatric Oncology Patients and Families), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
14.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05876325 nacompletednot on this map

Leveraging Medical Legal Partnerships to Enhance Patient-Centered, Team-Based Cost Conversations With Pediatric Oncology Patients and Families

TypeinterventionalSponsorJean EdwardRan2021 to 2022Enrolled61ConditionsFinancial Stress, Pediatric CancerArmsFINassist Patient, FINassist Caregiver
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jean EdwardCollege of Nursing, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0001-9184-1048
Kimberly D NorthripDepartment of Pediatrics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Mary Kay RayensCollege of Nursing, University of Kentucky, Lexington, Kentucky, USA.
Andrea WelkerDepartment of Pediatrics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Rachel O'FarrellDanceblue Pediatric Hematology Oncology Clinic, Kentucky Children's Hospital, University of Kentucky HealthCare, Lexington, Kentucky, USA.
Jennifer KnufDanceblue Pediatric Hematology Oncology Clinic, Kentucky Children's Hospital, University of Kentucky HealthCare, Lexington, Kentucky, USA.
Haafsah FariduddinMarkey STRONG, Markey Cancer Center, University of Kentucky HealthCare, Lexington, Kentucky, USA.
Julia CostichDepartment of Health Management and Policy, College of Public Health, University of Kentucky, Lexington, Kentucky, USA.
John D'OrazioDepartment of Pediatrics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
University of Kentucky · USUniversity of Kentucky HealthCare · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
NCI NIH HHS P30 CA177558Robert Wood Johnson Foundation 77293
6 · The paper itself

Abstract

backgroundPediatric, adolescent, and young adult patients with cancer and their caregivers are at high risk of financial toxicity, and few evidence-based oncology financial and legal navigation programs exist to address it. We tested the feasibility, acceptability, and preliminary effectiveness of Financial and Insurance Navigation Assistance, a novel interdisciplinary financial and legal navigation intervention for pediatric, adolescent and young adult patients and their caregivers.

methodsWe used a single-arm feasibility and acceptability trial design in a pediatric hematology and oncology clinic and collected preintervention and postintervention surveys to assess changes in financial toxicity (3 domains: psychological response/Comprehensive Score for Financial Toxicity [COST], material conditions, and coping behaviors); health-related quality of life (Patient-Reported Outcomes Measurement Information System Physical and Mental Health, Anxiety, Depression, and Parent Proxy scales); and perceived feasibility, acceptability, and appropriateness.

resultsIn total, 45 participants received financial navigation, 6 received legal navigation, and 10 received both. Among 15 adult patients, significant improvements in FACIT-COST (P = .041) and physical health (P = .036) were noted. Among 46 caregivers, significant improvements were noted for FACIT-COST (P < .001), the total financial toxicity score (P = .001), and the parent proxy global health score (P = .0037). We were able to secure roughly $335 323 in financial benefits for 48 participants. The intervention was rated highly for feasibility, acceptability, and appropriateness.

conclusionsIntegrating financial and legal navigation through Financial and Insurance Navigation Assistance was feasible and acceptable and underscores the benefit of a multidisciplinary approach to addressing financial toxicity. CLINICALTRIALS.GOV REGISTRATION: NCT05876325.

Indexed as

CaregiversFeasibility StudiesNeoplasmsQuality of LifeAdaptation, PsychologicalAdolescentAdultAnxietyChildCost of IllnessDepressionFemaleHumansInsurance, HealthMalePatient Navigation

Identifiers

PMID38552323
PMCPMC11087728
OpenAlexW4393347648

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.