SynthesisPloS one2024
A systematic review of risk factors associated with depression and anxiety in cancer patients.
Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Diagnostic Prediction Models for Depression in Patients With Breast Cancer: A Systematic Review.Journal of clinical nursing · 2026Pooled it
- Machine Learning Models for Predicting Pain, Fatigue, Depression, Anxiety, and Malnutrition in Cancer Patients: A Systematic Review and Meta-Analysis.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2026Pooled it
- The effectiveness of guided imagery on psychological outcomes and quality of life in cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Evaluating the effectiveness of psilocybin in alleviating distress among cancer patients: A systematic review.Palliative & supportive care · 2025Pooled it
- Psychological Distress in Bladder Cancer Patients: A Systematic Review.Cancer medicine · 2024Pooled it
- Psychosocial Well-Being and Care Among Advanced Cancer Patients: A Multi-Country Southeast Asia Study.Psycho-oncology · 2026Article
- Cancer-Related Psychological Distress over the Past Decade: A Bibliometric Analysis of Research Trends, Hotspots, and Emerging Areas.Healthcare (Basel, Switzerland) · 2026Review
- Mental illness and health literacy in people with cancer: the Australian National Health Survey analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Association between socioeconomic position and transitions to multimorbidity involving major chronic diseases in Northwest Italy.npj aging · 2026Article
- Pharmacotherapeutic Management of Depression in Patients With Cancer: A Review of Mechanistic and Clinical Evidence.Cancer reports (Hoboken, N.J.) · 2026Review
- Holding it together: a longitudinal study of psychological distress and associated factors in mothers with cancer.BMC psychology · 2026Observational
- Analysis the incidence and related risk factors of depression in patients with esophageal cancer combined with bone metastasis.World journal of psychiatry · 2026Article
- Beyond survival: the hidden impact of depression on life after cancer.Journal of cancer survivorship : research and practice · 2026Article
- Modifiable psychosocial risk factors for depression among cancer survivors in the United States.PloS one · 2026Article
- Dynamic disease progression in non-metastatic nasopharyngeal carcinoma post-radical radiotherapy: a Markov model-based analysis in a Chinese cohort.Therapeutic advances in medical oncology · 2026Article
- Psychological and physical distress in patients with advanced cancer after the COVID-19 pandemic: a cross-sectional study.Scientific reports · 2025Article
- Analysis of anticancer drug associated adverse reactions in depressive patients from vigibase.Scientific reports · 2025Article
- Emotional stress: a prominent factor positively related to the onset and recurrence of bladder cancer as revealed by NHANES and a Chinese database.Annals of medicine · 2025Article
- Causal Relationship Between Anxiety Disorders and Cancers: A Bidirectional Two-Sample Mendelian Randomization Study.Brain and behavior · 2025Article
- Prevalence and Associated Factors for Depression Among Patients With Sarcoma.JCO oncology practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression and anxiety are common comorbid conditions associated with cancer, however the risk factors responsible for the onset of depression and anxiety in cancer patients are not fully understood. Also, there is little clarity on how these factors may vary across the cancer phases: diagnosis, treatment and depression. We aimed to systematically understand and synthesise the risk factors associated with depression and anxiety during cancer diagnosis, treatment and survivorship. We focused our review on primary and community settings as these are likely settings where longer term cancer care is provided. We conducted a systematic search on PubMed, PsychInfo, Scopus, and EThOS following the PRISMA guidelines. We included cross-sectional and longitudinal studies which assessed the risk factors for depression and anxiety in adult cancer patients. Quality assessment was undertaken using the Newcastle-Ottawa assessment checklists. The quality of each study was further rated using the Agency for Healthcare Research and Quality Standards. Our search yielded 2645 papers, 21 of these were eligible for inclusion. Studies were heterogenous in terms of their characteristics, risk factors and outcomes measured. A total of 32 risk factors were associated with depression and anxiety. We clustered these risk factors into four domains using an expanded biopsychosocial model of health: cancer-specific, biological, psychological and social risk factors. The cancer-specific risk factors domain was associated with the diagnosis, treatment and survivorship phases. Multifactorial risk factors are associated with the onset of depression and anxiety in cancer patients. These risk factors vary across cancer journey and depend on factors such as type of cancer and individual profile of the patients. Our findings have potential applications for risk stratification in primary care and highlight the need for a personalised approach to psychological care provision, as part of cancer care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.