ReviewUrologia2024
Elderly and bladder cancer: The role of radical cystectomy and orthotopic urinary diversion.
Review in Urologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Sexual life and intimate relationship experience among bladder cancer patients: a systematic review and qualitative meta-synthesis.Frontiers in public health · 2026Pooled it
- Review
- Perioperative outcomes following open radical cystectomy in the setting of locally advanced bladder cancer.International urology and nephrology · 2026Observational
- Development and internal validation of an explainable machine-learning model to predict 3-year overall survival rate after radical cystectomy.BMC cancer · 2026Article
- Female Sexual Function After Radical Treatment for MIBC: A Systematic Review.Journal of personalized medicine · 2025Review
- The effect of different adipose tissue measurements on clinical prognosis in bladder cancer patients undergoing radical cystectomy: preliminary results.Abdominal radiology (New York) · 2025Article
- Multi-machine learning model based on radiomics features to predict prognosis of muscle-invasive bladder cancer.BMC cancer · 2025Article
- Enhanced prognostic prediction of cancer-specific mortality in elderly bladder cancer patients post-radical cystectomy: an XGBoost model study.Translational cancer research · 2025Article
- Using machine learning for predicting cancer-specific mortality in bladder cancer patients undergoing radical cystectomy: a SEER-based study.BMC cancer · 2025Article
- Survival analysis comparing bladder preservation techniques in octogenarians with muscle-invasive bladder cancer.Translational andrology and urology · 2025Article
- Predicting 90-day risk of urinary tract infections following urostomy in bladder cancer patients using machine learning and explainability.Scientific reports · 2025Article
- Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer.World journal of surgical oncology · 2025Article
- The mental and emotional status after radical cystectomy and different urinary diversion orthotopic bladder substitution versus external urinary diversion after radical cystectomy: A propensity score-matched study.International journal of urology : official journal of the Japanese Urological Association · 2024Observational
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of bladder cancer (BC) depends on advancing age and other risk factors, significantly impacting on surgical, functional and oncological outcomes. Radical cystectomy (RC) with urinary diversion is the gold standard therapy for muscle invasive bladder cancer; however, it remains a complex surgery and requires careful analysis of risk factors in order to potentially decrease post-surgical complication rates. Age in surgery is a limiting factor that can modify surgical and oncological outcomes, and is correlated with a high rate of post-dimssion hospital readmissions. The reconstruction of the bladder with the intestine represents a crucial point of radical cystectomy and the urinary derivation (UD) is at the center of many debates. A non-continent UD seems to be the best choice in elderly patients (>75 years old), while orthotopic neobladder (ON) is poorly practiced. We reviewed the literature to identify studies reporting outcomes, complications, patient- selection criteria, and quality-of-life data on elderly patients, who underwent ON following radical cystectomy. Reviewing the literature there is no clear evidence on the use of age as an exclusion criterion. Certainly, the elderly patient with multiple comorbidities is not eligible for ON, preferring other UD or rescue therapies. A careful preoperative selection of elderly patients could greatly improve clinical, surgical and oncological outcomes, giving the chance to selected patients to receive an ON.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.