Evidence map›Paper›PMID 38550684›Full record

ArticleChemical science2024

Mitochondria-targeting biocompatible fluorescent BODIPY probes.

Edward R H Walter, Lawrence Cho-Cheung Lee, Peter Kam-Keung Leung, Kenneth Kam-Wing Lo, Nicholas J Long

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Mitochondria-Targeting Moieties Based on N-Tethered Pyridinium Cations.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Review
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  5. Review
  6. Development and evaluation of mitochondria-targeted caseinolytic protease (ClpP) agonist chemical probes in in vitro breast cancer models.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Edward R H WalterDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub London W12 0BZ UK n.long@imperial.ac.uk.ORCID https://orcid.org/0000-0002-1396-3928
Lawrence Cho-Cheung LeeLaboratory for Synthetic Chemistry and Chemical Biology Limited Units 1503-1511, 15/F, Building 17 W, Hong Kong Science Park, New Territories Hong Kong P. R. China.ORCID https://orcid.org/0000-0002-5046-0676
Peter Kam-Keung LeungDepartment of Chemistry, City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong P. R. China.ORCID https://orcid.org/0000-0002-6050-5276
Kenneth Kam-Wing LoDepartment of Chemistry, City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong P. R. China.ORCID https://orcid.org/0000-0002-2470-5916
Nicholas J LongDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub London W12 0BZ UK n.long@imperial.ac.uk.ORCID https://orcid.org/0000-0002-8298-938X
City University of Hong Kong · HKImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increase in the mitochondrial membrane potential (MMP) is a characteristic feature of cancer and cardiovascular disease. Therefore, it remains of crucial importance to develop new and improved fluorescent probes that are sensitive to the MMP, to report on mitochondrial health and function. Reported here are the design, synthesis, photophysical properties and biological characterisation of a series of BODIPY dyes, BODIPY-Mito-

Identifiers

PMID38550684
PMCPMC10966975
OpenAlexW4392006985

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.