Evidence map›Paper›PMID 38550623›Full record

ArticleProceedings. IEEE International Conference on Bioinformatics and Biomedicine2022

A Latent Space Model for HLA Compatibility Networks in Kidney Transplantation.

Zhipeng Huang, Kevin S Xu

Open access · greenAbstract read
In one paragraph

Article in Proceedings. IEEE International Conference on Bioinformatics and Biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zhipeng HuangDepartment of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106 USA.
Kevin S XuDepartment of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106 USA.
Case Western Reserve University · US

Funding

Machine Learning and Network Science for Predicting Kidney Transplant Survival R01LM013311 · NLM · UNIVERSITY OF TOLEDO · PI STEPKOWSKI, STANISLAW M, XU, KEVIN SHUAI · 2019 to 2021
$830k
NLM NIH HHS R01 LM013311
6 · The paper itself

Abstract

Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to grant failure, or graft survival time, can vary significantly between different recipients. A significant biological factor affecting graft survival times is the compatibility between the human leukocyte antigens (HLAs) of the donor and recipient. We propose to model HLA compatibility using a network, where the nodes denote different HLAs of the donor and recipient, and edge weights denote compatibilities of the HLAs, which can be positive or negative. The network is

Indexed as

biological networkCox proportional hazardsgraft survivalhuman leukocyte antigensindirectly-observed networksigned networksurvival analysisweighted network

Identifiers

PMID38550623
PMCPMC10977095
OpenAlexW4313413231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.