Evidence map›Paper›PMID 38550439›Full record

ArticleCureus2024

An Unusual Case of Apixaban-Induced Small Vessel Vasculitis: Leukocytoclastic Vasculitis.

Abigail Y Adebayo, Azka Ali, Roshan M Goswami, Oluwatosin Abimbolu, Khudija Nayab, Henry Onyemarim

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 5 countries.

Abigail Y AdebayoEmergency Medicine, Glangwili General Hospital, Wales, GBR.
Azka AliInternal Medicine, Rosalind Franklin University of Medicine and Science, North Chicago, USA.
Roshan M GoswamiInternal Medicine, American University of Antigua, Antigua, ATG.
Oluwatosin AbimboluFamily Medicine, St Helen's and Knowsley NHS Trust, Coventry, GBR.
Khudija NayabInternal Medicine, Khyber Girls Medical College, Peshawar, PAK.
Henry OnyemarimPathology and Laboratory Medicine, Asaba Specialist Hospital, Asaba, NGA.
Khyber Girls Medical CollegeAmerican University of Antigua · AGCorporación para el Desarrollo Sostenible del Urabá · CORosalind Franklin University of Medicine and Science · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apixaban is a rare cause of drug-induced leukocytoclastic vasculitis (LCV). We report a case of apixaban-induced LCV in a 55-year-old male with deep vein thrombosis who developed systemic symptoms and pruritic rash in the bilateral lower extremity after 17 days of apixaban therapy. A skin biopsy confirmed the LCV, and he was diagnosed with apixaban-induced LCV after ruling out all other possible causes. His condition improved after apixaban discontinuation, supportive management, and oral prednisone. Our case highlights the early diagnosis and management of drug-induced LCV and also describes the existing literature to highlight existing knowledge and potential mechanisms underlying anticoagulant-induced vasculitis.

Indexed as

apixaban induced leukocytoclastic vasculitisdirect oral anticoagulant side effectdrug-induced hypersensitivitylcvleukocytoclastic vasculitis (lcv)

Identifiers

PMID38550439
PMCPMC10977000
OpenAlexW4392199789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.