Evidence map›Paper›PMID 38550408›Full record

ArticleCureus2024

Recurrent Lactobacillus Rhamnoses Bacteremia and Complications in an Immunocompromised Patient With History of Probiotic Use: A Case Report.

Ujunwa J Eze, Anthony Lal, Menatallah I Elkoush, Marta Halytska, Syed Atif

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Postbiotics: an insightful review of the latest category in functional biotics.World journal of microbiology & biotechnology · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ujunwa J EzeFamily Medicine, WellSpan Good Samaritan Hospital, Lebanon, USA.
Anthony LalFamily Medicine, WellSpan Good Samaritan Hospital, Lebanon, USA.
Menatallah I ElkoushFamily Medicine, WellSpan Good Samaritan Hospital, Lebanon, USA.
Marta HalytskaFamily Medicine, WellSpan Good Samaritan Hospital, Lebanon, USA.
Syed AtifFamily Medicine, WellSpan Good Samaritan Hospital, Lebanon, USA.
Good Samaritan Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of probiotics has been on the rise in the past few years. Increasing reports on Lactobacillus bacteremia-associated morbidity and mortality in immunocompromised patients have raised safety concerns about its use in this group. We present a case of a 79-year-old patient with a history of probiotic use who was admitted from the emergency department for acute-on-chronic diarrhea, acute hyponatremia, acute-on-chronic diastolic heart failure, and ambulatory dysfunction. His multiple co-morbidities include stage III chronic kidney disease, type II diabetes mellitus, chronic diastolic heart failure, Parkinson's disease, essential hypertension, atrial fibrillation, status post pacemaker placement, and status post bioprosthetic aortic valve replacement. He was diagnosed with a resistant case of Lactobacillus bacteremia during his admission, with multiple positive blood cultures positive for L. rhamnosus resistant to antibiotics therapy. Unfortunately, due to multiple complications related to Lactobacillus bacteremia, he transitioned to comfort care and ultimately passed away in a few weeks. Although probiotics are generally considered safe, their safety in immunocompromised patients is uncertain. Until more research is available to confirm their safety, caution should be taken when using them in this population. This study is an addendum to the few studies on this topic.

Indexed as

immunosuppressionlactobacillus bacteremia–associated morbiditylactobacillus infectionslactobacillus rhamnoses bacteremiaprobiotics

Identifiers

PMID38550408
PMCPMC10976466
OpenAlexW4392140201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.