Evidence map›Paper›PMID 38549795›Full record

ReviewRSC advances2024

Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration.

Pakeeza, Muhammad Umar Draz, Asim Yaqub, Ali Turab Jafry, Majid Khan, Huma Ajab

Open access · goldAbstract readReview
In one paragraph

Review in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Functional characterization of vitamin BFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

PakeezaDepartment of Chemistry, COMSATS University Islamabad Abbottabad Campus Pakistan pakeezanaveed222@gmail.com humaajab@cuiatd.edu.pk muhammad.umar115@amalacademy.org.
Muhammad Umar DrazDepartment of Chemistry, COMSATS University Islamabad Abbottabad Campus Pakistan pakeezanaveed222@gmail.com humaajab@cuiatd.edu.pk muhammad.umar115@amalacademy.org.
Asim YaqubDepartment of Environmental Sciences, COMSATS University Islamabad Abbottabad Campus Pakistan asimyaqub@cuiatd.edu.pk.
Ali Turab JafryFaculty of Mechanical Engineering, GIK Institute of Engineering Sciences & Technology Topi, District Swabi KPK 23640 Pakistan.ORCID https://orcid.org/0000-0002-0976-175X
Majid KhanCentralized Resource Lab, University of Peshawar Pakistan majidcrl@uop.edu.pk.
Huma AjabDepartment of Chemistry, COMSATS University Islamabad Abbottabad Campus Pakistan pakeezanaveed222@gmail.com humaajab@cuiatd.edu.pk muhammad.umar115@amalacademy.org.ORCID https://orcid.org/0000-0002-2305-4648
COMSATS University Islamabad · PKGhulam Ishaq Khan Institute of Engineering Sciences and Technology · PKUniversity of Peshawar · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamins are crucial micronutrients found in limited quantities in food, living organisms, and soil. Since most vitamins are not produced within the human body, a lack of these essential nutrients can result in various physiological disorders. Analyzing vitamins typically involves costly, time-consuming methods, requiring skilled personnel, automated equipment, and dedicated laboratory setups. The pressing need is for the development of efficient, portable, and user-friendly detection techniques that are cost-effective, addressing the challenges associated with traditional analytical approaches. In recent years, electrochemical sensors and electrochemical microfluidic devices have garnered prominence owing to their remarkable sensitivity, quick analysis, cost-effectiveness, and facile fabrication procedures. Electrochemical sensing and microfluidics are two distinct fields that are often integrated to create powerful and versatile sensing devices. The connection between them leverages the advantages of both fields to create highly efficient, miniaturized, and portable analytical systems. This interdisciplinary approach has led to the development of innovative devices with broad applications in various scientific, medical, and environmental domains. This review begins by outlining the importance of vitamins in human nutrition and health and emphasizing the need for precise and reliable sensing techniques. Owing to the limited literature available on electrochemical detection of vitamin B complexes, this review offers an in-depth analysis of modern electrochemical sensing of water-soluble vitamins, focusing on B1, B2, B6, B9, and B12. The challenges faced by researchers are addressed, including selectivity, sensitivity, interference, matrix effects, and calibration, while also exploring promising prospects such as nanomaterial integration, miniaturization, microfluidics-based IoTs, and innovative sensor designs.

Identifiers

PMID38549795
PMCPMC10977047
OpenAlexW4393258885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.