Evidence map›Paper›PMID 38549727›Full record

ReviewGlobal heart2024

Decentralization and Integration of Advanced Cardiac Care for the World's Poorest Billion Through the PEN-Plus Strategy for Severe Chronic Non-Communicable Disease.

Sheila L Klassen, Emmy Okello, Jose M E Ferrer, Faraz Alizadeh, Prebo Barango, Pilly Chillo, Yamikani Chimalizeni, Wubaye Walelgne Dagnaw, Jean-Luc Eiselé, Lauren Eberly and 21 more

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Global heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 14 countries.

Sheila L Klassen *Center for Integration Science, Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, United States.ORCID 0000-0002-7065-6668
Emmy Okello *Department of Medicine, Makerere University, Kampala, Uganda.ORCID 0000-0002-6109-0092
Jose M E FerrerAmerican Heart Association International, Dallas, United States.
Faraz AlizadehDepartment of Cardiology, Boston Children's hospital, Boston, United States.ORCID 0000-0001-9452-4566
Prebo BarangoWorld Health Organization, Regional Office for Africa, Brazzaville, Republic of Congo.ORCID 0000-0001-9498-8053
Pilly ChilloMuhimbili University of Health and Allied Sciences, Department of Internal Medicine, Dar Es Salaam, Tanzania.ORCID 0000-0001-7073-1122
Yamikani ChimalizeniKamuzu University of Health Sciences, Queen Elizabeth Central Hospital, Blantyre, Malawi.ORCID 0000-0003-0119-804X
Wubaye Walelgne DagnawCenter for Integration Science, Division of Global Health Equity, Brigham and Women's Hospital, Boston, United States.ORCID 0000-0001-5894-810X
Jean-Luc EiseléWorld Heart Federation, Geneva, Switzerland.
Lauren EberlyDivision of Cardiovascular Medicine, Department of Medicine, Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, Cardiovascular Institute, Penn Cardiovascular Center for Health, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0003-0879-7694
Anu GomanjuKathmandu Institute of Child Health, Kathmandu, Nepal.ORCID 0000-0001-8052-5517
Neil GuptaCenter for Integration Science, Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, United States.ORCID 0000-0003-3470-5351
Bhagawan KoiralaDepartment of Cardiothoracic & Vascular Surgery - Manmohan Cardiothoracic Vascular and Transplant Centre, Kathmandu, Nepal.ORCID 0000-0001-5537-0031
Jacques KpodonuDivision of Cardiac Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, United States.ORCID 0000-0001-7222-2786
Gene KwanSection of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, United States.ORCID 0000-0002-0929-6800
Bright G D MailosiPartners In Health/Abwenzi Pa Za Umoyo, Neno, Malawi.ORCID 0000-0001-9089-0163
Lilian MbauKenya Cardiac Society, Nairobi, Kenya.ORCID 0000-0003-2086-4562
Reuben MutagaywaDepartment of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.ORCID 0000-0002-0928-8149
Colin PfaffCenter for Integration Science, Division of Global Health Equity, Brigham and Women's Hospital, Boston, United States.ORCID 0000-0003-1881-9113
Daniel PiñeroDepartamento de Ecología Evolutiva, Instituto de Ecología, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.ORCID 0000-0002-2509-2445
Fausto PintoCardiology Department, Centro Hospitalar Universitário Lisboa Norte, CAML, CCUL, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0002-8034-4529
Emmanuel RusingizaDepartment of Pediatrics, Pediatric Cardiology Unit, University Teaching Hospital of Kigali, Kigali, Rwanda.ORCID 0000-0003-2296-7645
Usman Abiola SanniPartners in Health, Sierra Leone.
Amy SanyahumbiPediatric Cardiology, Baylor College of Medicine, Texas Children's Hospital, Houston, United States.ORCID 0000-0002-5545-5729
Urmila ShakyaPediatric Cardiology Department, Shahid Gangalal National Heart Centre, Kathmandu, Nepal.
Sanjib Kumar SharmaCardiology and Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.ORCID 0000-0002-8392-8028
Kunjang SherpaDepartment of Cardiology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.ORCID 0000-0003-1136-6983
Isaac SinabulyaDepartment of Medicine, Makerere University, College of Health Sciences, Kampala, Uganda.
Emily B WroeCenter for Integration Science, Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, United States.ORCID 0000-0002-9152-9553
Gene Bukhman *Center for Integration Science, Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, United States.ORCID 0000-0003-4500-7903
Ana Mocumbi *Universidade Eduardo Mondlane, Maputo, Mozambique.ORCID 0000-0002-9564-2860
Brigham and Women's Hospital · USMakerere University · UGMuhimbili University of Health and Allied Sciences · TZAdult Congenital Heart Association · USAmerican Heart Association · USBaylor College of Medicine · USBeth Israel Deaconess Medical Center · USBir Hospital · NPBoston Children's Hospital · USBoston University · USB.P. Koirala Institute of Health Sciences · NPCardiovascular Institute of the South · USEduardo Mondlane University · MZInstituto de Ecología · MXManmohan Memorial Institute of Health Sciences · NPPartners In Health · USQueen Elizabeth Central Hospital · MWShahid Gangalal National Heart Centre · NPUniversity of Kigali · RWUniversity of Lisbon · PT

Funding

Identifying facilitators and barriers to heart failure care in Haiti to adapt a community-based interventionK23HL140133 · NHLBI · BOSTON MEDICAL CENTER · PI KWAN, GENE FAZIL · 2019 to 2022
$663k
Simulator-Based simplified Focused Cardiac Ultrasound (sFoCUS) Training in HaitiR21TW012165 · FIC · BOSTON MEDICAL CENTER · PI KWAN, GENE FAZIL · 2022 to 2023
$478k
American Heart Association-American Stroke Association 192269FIC NIH HHS R21 TW012165NHLBI NIH HHS K23 HL140133World Health Organization 001
6 · The paper itself

Abstract

Rheumatic and congenital heart disease, cardiomyopathies, and hypertensive heart disease are major causes of suffering and death in low- and lower middle-income countries (LLMICs), where the world's poorest billion people reside. Advanced cardiac care in these counties is still predominantly provided by specialists at urban tertiary centers, and is largely inaccessible to the rural poor. This situation is due to critical shortages in diagnostics, medications, and trained healthcare workers. The Package of Essential NCD Interventions - Plus (PEN-Plus) is an integrated care model for severe chronic noncommunicable diseases (NCDs) that aims to decentralize services and increase access. PEN-Plus strategies are being initiated by a growing number of LLMICs. We describe how PEN-Plus addresses the need for advanced cardiac care and discuss how a global group of cardiac organizations are working through the PEN-Plus Cardiac expert group to promote a shared operational strategy for management of severe cardiac disease in high-poverty settings.

Indexed as

HypertensionNoncommunicable DiseasesHumansPoliticsadvanced cardiac diseasedecentralizationheart failurelow-income country

Identifiers

PMID38549727
PMCPMC10976983
OpenAlexW4393240177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.