Evidence map›Paper›PMID 38549574›Full record

ArticleOpen veterinary journal2024

Liver histopathological and oxidative stress assessment by a combination of formaldehyde and oxytetracycline in sea bass (

Zouhour Ouanes-Ben Othmen, Mohamed Ali Jerbi, Rim Timoumi, Raouf Besbes, Zohra Haouas, Lotfi Achour, Altayeb Elazomi, Abdurraouf Zaet, Lazhar Zourgui, Adnen Kacem

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zouhour Ouanes-Ben OthmenFaculty of Sciences, Research Laboratory of Environmental Chemistry and Clean Processes, LR21ES04, Monastir University, Monastir, Tunisia.
Mohamed Ali JerbiHigher Institute of Biotechnology of Monastir, Genome Laboratory, Immune Diagnostic and Valorization 03/UR/09-01, Monastir University, Monastir, Tunisia.
Rim TimoumiFaculty of Dental Medicine, Laboratory for Research on Biologically Compatible Compounds (LRSBC), LR 01SE17, Monastir University, Monastir, Tunisia.
Raouf BesbesNational Institute of Science and Technology of the Sea, Monastir, Tunisia.
Zohra HaouasLaboratory of Histology and Cytogenetics, Faculty of Medicine, Monastir University, Monastir, Tunisia.
Lotfi AchourHigher Institute of Biotechnology of Monastir, Genome Laboratory, Immune Diagnostic and Valorization 03/UR/09-01, Monastir University, Monastir, Tunisia.
Altayeb ElazomiFaculty of Medical Technology, University of Zawia, Zawia, Libya.
Abdurraouf ZaetFaculty of Medical Technology, University of Zawia, Zawia, Libya.
Lazhar ZourguiResearch Laboratory BMA "Biodiversity, Molecules, Application", Higher Institute of Applied Biology Medenine, Gabes University, Gabes, Tunisia.
Adnen KacemHigher Institute of Biotechnology of Monastir, Genome Laboratory, Immune Diagnostic and Valorization 03/UR/09-01, Monastir University, Monastir, Tunisia.
Al Zawiya University · LY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Formaldehyde (FA) and oxytetracycline (OTC) are the chemicals commonly used in aquaculture to prevent or treat fish diseases due to protozoa, parasites, and bacteria. Aim: The goal of the present study is to assess the liver injury and oxidative stress induced by exposure of sea bass ( Methods: The liver histopathological survey was achieved after 5 and 10 days of exposure to FA, OTC separately or mixed. In parallel, liver catalase activity and malondialdehyde (MDA) were measured to assess oxidative stress. Results: Results showed that treatment with FA and OTC used alone or in combinations induced liver damage as measured by sinusoid dilatation, intensive vacuolization, blood congestion, and focal necrosis. Significant elevation in catalyze activity and MDA levels were also observed in liver homogenates by the treatment ( Conclusion: Combined treatment induced higher effects suggesting the critical hazards associated with FA and OTC when released to the environment.

Indexed as

BassOxytetracyclineAnimalsFormaldehydeLiverOxidative StressFormaldehydeOxytetracyclineFormaldehydeLiver histopathologyOxidative damageOxytetracyclineSea bass

Identifiers

PMID38549574
PMCPMC10970122
OpenAlexW4392744180

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.