Evidence map›Paper›PMID 38548965›Full record

ArticleCommunications biology2024

Kir4.1 channels contribute to astrocyte CO

Colin M Cleary, Jack L Browning, Moritz Armbruster, Cleyton R Sobrinho, Monica L Strain, Sarvin Jahanbani, Jaseph Soto-Perez, Virginia E Hawkins, Chris G Dulla, Michelle L Olsen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Colin M ClearyDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0003-0305-1324
Jack L BrowningSchool of Neuroscience and Genetics, Genomics and Computational Biology, Virginia Tech, Blacksburg, VA, USA.ORCID 0000-0002-3102-0667
Moritz ArmbrusterDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, USA.ORCID 0000-0003-2341-513X
Cleyton R SobrinhoDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-1472-7169
Monica L StrainDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Sarvin JahanbaniSchool of Neuroscience and Genetics, Genomics and Computational Biology, Virginia Tech, Blacksburg, VA, USA.
Jaseph Soto-PerezDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Virginia E HawkinsDepartment of Life Sciences, Manchester Metropolitan University, Manchester, UK.ORCID 0000-0001-9505-6776
Chris G DullaDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, USA.
Michelle L OlsenSchool of Neuroscience and Genetics, Genomics and Computational Biology, Virginia Tech, Blacksburg, VA, USA.ORCID 0000-0003-1394-664X
Daniel K MulkeyDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA. daniel.mulkey@uconn.edu.ORCID 0000-0002-7040-3927
University of Connecticut · USVirginia Tech · USTufts University · USManchester Metropolitan University · GB

Funding

Glial chemosensitivity: pH sensing and interactions with neuronal chemoreceptorsR01HL104101 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, OLSEN, MICHELLE L · 2010 to 2024
$5.5M
Role of KCNQ2 Channels in Control of BreathingR01HL137094 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, TZINGOUNIS, ANASTASIOS · 2018 to 2025
$4.1M
Voltage Imaging of Astrocyte-Neuron InteractionsR01NS113499 · NINDS · TUFTS UNIVERSITY BOSTON · PI DULLA, CHRIS G · 2019 to 2023
$3.7M
Atypical astrocytes in aging and Alzheimer's DiseaseR01AG085666 · NIA · TUFTS UNIVERSITY BOSTON · PI Chris G Dulla · 2024 to 2026
$2.5M
Molecular signature of parafacial expiratory neuronsR21NS134132 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K · 2023 to 2023
$443k
Contributions of Astrocyte Kir4.1/5.1 Channels to Disordered Breathing in Rett SyndromeF31HL167553 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI Monica Strain · 2023 to 2026
$184k
Proposed roles of KCNQ2 Channels in Respiratory HomeostasisF31HL156470 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI SOTO, JASEPH · 2021 to 2024
$173k
Defining Astrocyte Heterogeneity in the Retrotrapezoid NucleusF32HL126381 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI HAWKINS, VIRGINIA · 2015 to 2016
$124k
Role of P2Y2 in the Regulation of Vascular Tone and Control of BreathingF31HL142227 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI CLEARY, COLIN · 2018 to 2020
$119k
NHLBI NIH HHS F31 HL142227NHLBI NIH HHS F31 HL156470NHLBI NIH HHS F31 HL167553NHLBI NIH HHS F32 HL126381NHLBI NIH HHS R01 HL104101NHLBI NIH HHS R01 HL137094NIA NIH HHS R01 AG085666NINDS NIH HHS R01 NS113499NINDS NIH HHS R21 NS134132
6 · The paper itself

Abstract

Astrocytes in the retrotrapezoid nucleus (RTN) stimulate breathing in response to CO

Indexed as

AstrocytesCarbon DioxideAnimalsMiceMice, KnockoutNeuronsRespirationCarbon Dioxide

Identifiers

PMID38548965
PMCPMC10978993
OpenAlexW4393262755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.