Evidence map›Paper›PMID 38548664›Full record

Trial reportEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2024

S erratus anterior plane block alone, paravertebral block alone and their combination in video-assisted thoracoscopic surgery: the THORACOSOPIC double-blind, randomized trial.

Florent Leviel, Alex Fourdrain, Florian Delatre, Florence De Dominicis, Thomas Lefebvre, Stéphane Bar, Hamza Yahia Alshatri, Emmanuel Lorne, Olivier Georges, Pascal Berna and 3 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04222010 (Serratus Plain Block Versus Paravertebral Block Versus Serratus Plain Block and Paravertebral Block for Postoperative Pain Following Thoracoscopic Surgery), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04222010 phase3completednot on this map

Serratus Plain Block Versus Paravertebral Block Versus Serratus Plain Block and Paravertebral Block for Postoperative Pain Following Thoracoscopic Surgery

TypeinterventionalSponsorCentre Hospitalier Universitaire, AmiensRan2020 to 2023Enrolled155ConditionsAnesthesia, Local, Pain, PostoperativeArmsloco-regional anesthesia serratus plane bloc (Ropivacaine 2 mg/mL, 40 mL) and paravertebral placebo bloc (saline, 20 mL), Loco-regional anesthesia : paravertebral bloc (Ropivacaine 4 mg/mL, 20 mL) and serratus plane placebo bloc (saline, 40 mL), Loco-regional anesthesia : serratus plane bloc (Ropivacaine 1,3 mg/mL, 40 mL) and paravertebral bloc (Ropivacaine 1,3 mg/mL, 20 mL)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Florent LevielDepartment of Anesthesia and Critical Care, Amiens Hospital University, Amiens, France.ORCID 0000-0001-6689-2492
Alex FourdrainDepartment of Thoracic Surgery, Marseille University Hospital, Marseille, France.ORCID 0000-0001-6431-3899
Florian DelatreDepartment of Anesthesia and Critical Care, Amiens Hospital University, Amiens, France.
Florence De DominicisDepartment of Thoracic Surgery, Amiens Hospital University, Amiens, France.ORCID 0009-0000-1189-9849
Thomas LefebvreDepartment of Anesthesia and Critical Care, Amiens Hospital University, Amiens, France.
Stéphane BarDepartment of Anesthesia and Critical Care, Amiens Hospital University, Amiens, France.ORCID 0000-0002-4630-5833
Hamza Yahia AlshatriFaculty of Medicine, Department of Anesthesia and Critical Care, University of Jeddah, Jeddah, Saudi Arabia.ORCID 0000-0002-6536-4177
Emmanuel LorneDepartment of Anesthesia and Critical Care Medicine, Millénaire Clinic, Montpellier, France.ORCID 0000-0001-6409-5449
Olivier GeorgesDepartment of Thoracic Surgery, Amiens Hospital University, Amiens, France.
Pascal BernaDepartment of Thoracic Surgery, Victor Pauchet Clinic, Amiens, France.ORCID 0000-0003-2856-4951
Hervé DupontDepartment of Anesthesia and Critical Care, Amiens Hospital University, Amiens, France.ORCID 0000-0002-5644-3412
Jonathan MeynierDepartment of Biostatistics, Amiens Hospital University, Amiens, France.ORCID 0000-0001-8649-2330
Osama Abou-ArabDepartment of Anesthesia and Critical Care, Amiens Hospital University, Amiens, France.ORCID 0000-0003-3766-716X
Centre Hospitalier Universitaire Amiens-Picardie · FRAssistance Publique Hôpitaux de Marseille · FRClinique du Millénaire · FRUniversity of Jeddah · SA

Funding

Amiens Hospital University
6 · The paper itself

Abstract

objectivesSerratus anterior plane block (SAPB) and paravertebral block (PVB) are well known to reduce pain levels after video-assisted thoracoscopic surgery (VATS). However, the relative efficacies of each block and a combination of the 2 have not been fully characterized. The objective of the present study was to assess the efficacy of PVB alone, SAPB alone and the combination of PVB and SAPB with regard to the occurrence and intensity of pain after VATS.

methodsWe conducted the THORACOSOPIC single-centre, double-blind, randomized trial in adult patients due to undergo elective VATS lung resection. The participants were randomized to PVB only, SAPB only and PVB + SAPB groups. The primary end-point was pain on coughing on admission to the postanaesthesia care unit. The secondary end-points were postoperative pain at rest and on coughing at other time points and the cumulative opioid consumption. Pain was scored on a visual analogue scale.

resultsOne-hundred and fifty-six patients (52 in each group) were included. On admission to the postanaesthesia care unit, the 3 groups did not differ significantly with regard to the pain on coughing: the visual analogue scale score was 3 (0-6), 4 (0-8) and 2 (0-6) in the PVB, SAPB and PVB + SAPB groups, respectively (P = 0.204). During postoperative care, the overall pain score was significantly lower in the SABP + PVP group at rest and on cough.

conclusionsThe combination of SABP + PVB could be beneficial for pain management in VATS in comparison to SABP or PVB alone.

Indexed as

Nerve BlockThoracic Surgery, Video-AssistedAdultAnalgesics, OpioidHumansPostoperative PainAnalgesics, OpioidPainParavertebral blockRegional anesthesiaSerratus anterior plane blockVideo-assisted thoracoscopic surgery

Identifiers

PMID38548664
PMCPMC10990687
OpenAlexW4393345306

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.