Evidence map›Paper›PMID 38548350›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

SPECT/CT Image-Derived Absorbed Dose to Red Marrow Correlates with Hematologic Toxicity in Patients Treated with [

Johan Blakkisrud, Avery B Peterson, Scott J Wildermann, Griffen Kingkiner, Ka Kit Wong, Chang Wang, Kirk A Frey, Caroline Stokke, Yuni K Dewaraja

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Dosimetry-Driven Personalization of Radiopharmaceutical Therapies: Evidence and Opportunities.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
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  5. Article
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  7. Article
  8. Article
  9. Multicycle Dosimetric Behavior and Dose-Effect Relationships in [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  10. Dosimetry Software for Theranostic Applications: Current Capabilities and Future Prospects.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Johan BlakkisrudDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan; johbla@ous-hf.no.
Avery B PetersonDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan.
Scott J WildermannDepartment of Nuclear Engineering and Radiologic Science, University of Michigan, Ann Arbor, Michigan.
Griffen KingkinerDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan.
Ka Kit WongDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan.
Chang WangDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan.
Kirk A FreyDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan.
Caroline StokkeDepartment of Physics and Computational Radiology, Oslo University Hospital, Oslo, Norway.
Yuni K DewarajaDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan.
University of Michigan · USOslo University Hospital · NOUniversity of Oslo · NO

Funding

Bringing Capacity for Theranostic Dosimetry Planning to the Nuclear Medicine ClinicR01CA240706 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEWARAJA, YUNI K · 2020 to 2024
$3.0M
NCI NIH HHS R01 CA240706
6 · The paper itself

Abstract

Hematologic toxicity, although often transient, is the most common limiting adverse effect during somatostatin peptide receptor radionuclide therapy. This study investigated the association between Monte Carlo-derived absorbed dose to the red marrow (RM) and hematologic toxicity in patients being treated for their neuroendocrine tumors.

Indexed as

Bone MarrowNeuroendocrine TumorsOctreotideOrganometallic CompoundsSingle Photon Emission Computed Tomography Computed TomographyAdultAgedFemaleHematologic DiseasesHumansMaleMiddle AgedMonte Carlo MethodRadiation DosageRadiometrylutetium Lu 177 dotatateOctreotideOrganometallic Compounds[177Lu]Lu-DOTATATEpeptide receptor radionuclide therapyradiopharmaceutical therapyred marrow dosimetrytheranostics

Identifiers

PMID38548350
PMCPMC11064826
OpenAlexW4393253290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.