Evidence map›Paper›PMID 38548347›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

High-Temporal-Resolution Kinetic Modeling of Lung Tumors with Dual-Blood Input Function Using Total-Body Dynamic PET.

Yiran Wang, Yasser G Abdelhafez, Benjamin A Spencer, Rashmi Verma, Mamta Parikh, Nicholas Stollenwerk, Lorenzo Nardo, Terry Jones, Ramsey D Badawi, Simon R Cherry and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Quantitative Total-Body Imaging of Blood Flow with High-Temporal-Resolution Early DynamicJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yiran WangDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Yasser G AbdelhafezDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Benjamin A SpencerDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Rashmi VermaComprehensive Cancer Center, University of California Davis Medical Center, Sacramento, California.
Mamta ParikhComprehensive Cancer Center, University of California Davis Medical Center, Sacramento, California.
Nicholas StollenwerkComprehensive Cancer Center, University of California Davis Medical Center, Sacramento, California.
Lorenzo NardoDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Terry JonesDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Ramsey D BadawiDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Simon R CherryDepartment of Radiology, University of California Davis Medical Center, Sacramento, California.
Guobao WangDepartment of Radiology, University of California Davis Medical Center, Sacramento, California; gbwang@ucdavis.edu.
University of California Davis Medical Center · USUniversity of California, Davis · USAssiut University · EG

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PETR01CA206187 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BADAWI, RAMSEY D., CHERRY, SIMON R · 2015 to 2019
$15.5M
UC Davis Paul Calabresi K12 Clinical Oncology Research Career Development ProgramK12CA138464 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BIRKELAND, ANDREW CHARLES, LARA, PRIMO N. · 2011 to 2025
$11.4M
Parametric PET of Neuroinflammation for NAFLD-related ADR01DK124803 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WANG, GUOBAO · 2020 to 2023
$2.6M
NCI NIH HHS K12 CA138464NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA206187NIDDK NIH HHS R01 DK124803
6 · The paper itself

Abstract

The lungs are supplied by both the pulmonary arteries carrying deoxygenated blood originating from the right ventricle and the bronchial arteries carrying oxygenated blood downstream from the left ventricle. However, this effect of dual blood supply has never been investigated using PET, partially because the temporal resolution of conventional dynamic PET scans is limited. The advent of PET scanners with a long axial field of view, such as the uEXPLORER total-body PET/CT system, permits dynamic imaging with high temporal resolution (HTR). In this work, we modeled the dual-blood input function (DBIF) and studied its impact on the kinetic quantification of normal lung tissue and lung tumors using HTR dynamic PET imaging.

Indexed as

Lung NeoplasmsPositron-Emission TomographyAdultAgedFemaleFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedKineticsMaleMiddle AgedModels, BiologicalPositron Emission Tomography Computed TomographyRadiopharmaceuticalsTime FactorsWhole Body ImagingFluorodeoxyglucose F18Radiopharmaceuticalsdual-blood input functionhigh temporal resolutionkinetic modelinglung cancertotal-body dynamic PET

Identifiers

PMID38548347
PMCPMC11064825
OpenAlexW4393279970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.