Evidence map›Paper›PMID 38548335›Full record

ArticleeNeuro2024

Ca

Xin Xia, Caleb Shi, Christina Tsien, Catalina B Sun, Lili Xie, Ziming Luo, Minjuan Bian, Kristina Russano, Hrishikesh Singh Thakur, Larry I Benowitz and 2 more

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Primary Cilia of Astrocytes in the Retina in Development and Disease.Investigative ophthalmology & visual science · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Xin XiaDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.ORCID https://orcid.org/0000-0002-6261-6690
Caleb ShiDepartment of Neurosurgery, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts 02115.
Christina TsienDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.
Catalina B SunDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.
Lili XieDepartment of Neurosurgery, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts 02115.
Ziming LuoDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.
Minjuan BianDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.
Kristina RussanoDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.
Hrishikesh Singh ThakurDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034.
Larry I BenowitzDepartment of Neurosurgery, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts 02115.ORCID https://orcid.org/0000-0002-0277-7222
Jeffrey L GoldbergDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034 kapiloff@stanford.edu jlgjournals@gmail.com.ORCID https://orcid.org/0000-0001-5104-8141
Michael S KapiloffDepartment of Ophthalmology, Byers Eye Institute, Mary M. and Sash A. Spencer Center for Vision Research, Stanford University School of Medicine, Palo Alto, California 94034 kapiloff@stanford.edu jlgjournals@gmail.com.
Vision Eye Institute · AUBoston Children's Hospital · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Gene Expression Regulatory Pathways and Retinal Ganglion Cell NeuroprotectionR01EY032416 · NEI · STANFORD UNIVERSITY · PI GOLDBERG, JEFFREY L, KAPILOFF, MICHAEL SETH · 2021 to 2024
$2.2M
VRC: The Role of Perinuclear cAMP in Retinal Ganglion Cell Neuroprotection and Optic Nerve RegenerationR01EY031167 · NEI · STANFORD UNIVERSITY · PI KAPILOFF, MICHAEL SETH · 2019 to 2021
$1.0M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY031167NEI NIH HHS R01 EY032416
6 · The paper itself

Abstract

Neuroprotection after injury or in neurodegenerative disease remains a major goal for basic and translational neuroscience. Retinal ganglion cells (RGCs), the projection neurons of the eye, degenerate in optic neuropathies after axon injury, and there are no clinical therapies to prevent their loss or restore their connectivity to targets in the brain. Here we demonstrate a profound neuroprotective effect of the exogenous expression of various Ca

Indexed as

Neurodegenerative DiseasesOptic Nerve DiseasesOptic Nerve InjuriesAnimalsAxonsCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell SurvivalMiceNerve RegenerationProtein IsoformsRetinal Ganglion CellsCalcium-Calmodulin-Dependent Protein Kinase Type 2Protein IsoformsCaMKIIglaucomaneuroprotectionoptic nerve injuryretinal ganglion cells

Identifiers

PMID38548335
PMCPMC10978821
OpenAlexW4393282393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.