ArticleJCO global oncology2024
Early-Onset Colorectal Cancer in Egypt: Pathological Characters, Patterns of Care, and Survival Compared to Average-Age Onset Colorectal Cancer: A Retrospective Multicenter Study.
Article in JCO global oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The burden and histopathological characteristics of early-onset colorectal cancer: a retrospective cross-sectional study at Ethiopia's largest tertiary hospital (2019-2024).International journal of colorectal disease · 2026Article
- Trends in gastrointestinal cancers at a major tertiary hospital in Alexandria, Egypt: a 10-year retrospective study (2010-2019).BMC gastroenterology · 2026Article
- Knowledge, Attitudes, and Practices Regarding Colorectal Cancer Screening Among Medical Residents: An Exploratory, Single-Center, Cross-Sectional Study from Egypt.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Analysis of volatile organic compounds in biological samples of colorectal cancer patients using electronic nose-based machine learning techniques.Scientific reports · 2025Article
- Review
- Epidemiologic and clinical profiles of colorectal cancer in Southern Egypt.BMC gastroenterology · 2025Article
- Early-onset gastrointestinal cancers: comprehensive review and future directions.The British journal of surgery · 2025Review
- Expression of VISTA on T cells in patients with cancer colon.Journal of the Egyptian National Cancer Institute · 2025Article
- Metagenomic analysis of gut microbiota in colorectal adenocarcinoma in the MENA region.Frontiers in cellular and infection microbiology · 2025Article
- Mapping the colorectal cancer patient journey in Egypt: A qualitative study of diagnosis, treatment, and lifestyle perspectives.PloS one · 2025Article
- Efficacy and safety of preoperative intravenous iron versus standard care in colorectal cancer patients with iron deficiency anemia: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Article
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18 authors.
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Abstract
purposeEarly-onset colorectal cancer (EOCRC) is a rising health problem. The incidence of EOCRC has increased over the past 2 decades all over the world. Reports from Egypt since the 1990s have reported a higher incidence among young populations with no identifiable risk factors. The aim of this study was to assess EOCRC in Egypt regarding incidence, characteristics, treatment pattern, and survival compared with average age onset and elderly patients. MATERIALS AND
methodsThis was a retrospective, record-based, cohort study combining data from four different cancer centers in Egypt. We grouped patients according to age into three categories: the EOCRC group for patients age ≤45 years and the average age onset and elderly cancer group (for patients age ≥65 years).
resultsThe study included 1,310 patients with histopathologically proven colorectal cancer, representing four different geographical areas in Egypt. Patients with EOCRC represented 42.4% of the study population. Female patients were 50.6% among the EOCRC group and 52.5% among the average age group. Rectal tumors were significantly higher in EOCRC (54.7%
conclusionA comprehensive framework for the study of EOCRC is required in Egypt as well as a genomic analysis to identify possible underlying genetic alterations responsible for the high incidence of EOCRC.
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