Evidence map›Paper›PMID 38547419›Full record

ArticleJCO precision oncology2024

Real-World Overall Survival and Treatment Patterns by

Shilpa Gupta, Tu My To, Ryon Graf, Edward E Kadel, Norelle Reilly, Husam Albarmawi

Open access · greenAbstract read
In one paragraph

Article in JCO precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shilpa GuptaTaussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH.ORCID 0000-0002-8775-503X
Tu My ToGenentech, Inc, South San Francisco, CA.ORCID 0000-0001-9506-7539
Ryon GrafFoundation Medicine, Inc, Cambridge, MA.ORCID 0000-0002-8065-4148
Edward E KadelGenentech, Inc, South San Francisco, CA.ORCID 0000-0003-3030-6628
Norelle ReillyGenentech, Inc, South San Francisco, CA.
Husam AlbarmawiGenentech, Inc, South San Francisco, CA.ORCID 0000-0001-8870-0842
Cleveland Clinic · USFoundation Medicine (United States)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt is estimated that the

methodsThis retrospective real-world cohort study used a deidentified US-based metastatic prostate cancer clinicogenomic database linked to longitudinal clinical data derived from electronic health records. Patients were aged 18 years and older and diagnosed with mCRPC between January 1, 2018, and June 30, 2021. Comprehensive genomic profiling (CGP) of tumor specimens was performed using next-generation sequencing. First-line (1L) and second-line (2L) treatment patterns were assessed and stratified by

resultsIn patients with mCRPC who underwent CGP,

conclusion

Indexed as

Prostatic Neoplasms, Castration-ResistantPTEN PhosphohydrolaseCohort StudiesHumansMalePrognosisRetrospective StudiesTreatment OutcomePTEN PhosphohydrolasePTEN protein, human

Identifiers

PMID38547419
PMCPMC10994466
OpenAlexW4393282830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.