Evidence map›Paper›PMID 38546927›Full record

ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2024

A rare clinical case of systemic AA amyloidosis with cardiac involvement complicating ankylosing spondylitis: a case report.

Leïla Barakat, Khadija Echchilali, Mina Moudatir, Hassan El Kabli, Yassine Ettagmouti, Mériem Haboub, Salim Arous, Mohamed Ghali Benouna, Abdenasser Drighil, Rachida Habbal and 5 more

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Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Leïla BarakatDepartment of Internal Medicine, CHU Ibn Rochd, Casablanca, Morocco. barakat.leila59@gmail.com.
Khadija EchchilaliDepartment of Internal Medicine, CHU Ibn Rochd, Casablanca, Morocco.
Mina MoudatirDepartment of Internal Medicine, CHU Ibn Rochd, Casablanca, Morocco.
Hassan El KabliDepartment of Internal Medicine, CHU Ibn Rochd, Casablanca, Morocco.
Yassine EttagmoutiCardiology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Mériem HaboubCardiology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Salim ArousCardiology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Mohamed Ghali BenounaCardiology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Abdenasser DrighilCardiology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Rachida HabbalCardiology Department, Ibn Rochd University Hospital, Casablanca, Morocco.
Meryame AzimLaboratory of Pathological Anatomy, CHU Ibn Rochd, Casablanca, Morocco.
Asmae MaztiLaboratory of Pathological Anatomy, CHU Ibn Rochd, Casablanca, Morocco.
Meriem RegraguiLaboratory of Pathological Anatomy, CHU Ibn Rochd, Casablanca, Morocco.
Nissrine Bennani GuebessiLaboratory of Pathological Anatomy, CHU Ibn Rochd, Casablanca, Morocco.
Mehdi KarkouriLaboratory of Pathological Anatomy, CHU Ibn Rochd, Casablanca, Morocco.
Centre Hospitalier Universitaire Ibn Rochd · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnkylosing spondylitis (AS) is a type of chronic inflammation that is most prevalent in young adults and is characterized by an inflammatory enthesiopathy that gradually develops toward ossification and ankylosis. If inflammation is left unchecked, it can potentially lead to complications such as secondary amyloidosis, also known as AA amyloidosis, involving the deposition of amyloid serum A protein. Our case presents with a thyroid localization of AA amyloidosis which is secondary to this AS. Such a case has been described in only four cases in the literature. Cardiac localization of AA amyloidosis has been exceptionally described in the literature. CASE PRESENTATION: We report the case of a young patient with severe AS complicated by secondary amyloidosis with thyroid, cardiac, and probably renal localization. He was treated with anti-TNF therapy, and his condition improved significantly.

conclusionsOur case presents several localizations of AA amyloidosis secondary to this AS. Although cardiac involvement is rare in secondary AA amyloidosis, it should always be screened for, even in a cardiacly asymptomatic patient.

Indexed as

Amyloid goitersAnkylosing spondylitisCardiac amyloidosisCase reportSecondary amyloidosis

Identifiers

PMID38546927
PMCPMC10978558
OpenAlexW4393260963

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.