Evidence map›Paper›PMID 38546861›Full record

ArticleSurgery today2024

Long-term survival and clinical outcomes of delayed chest closure following lung transplantation.

Takashi Hirama, Miki Akiba, Masahiro Ui, Saori Shibata, Fumiko Tomiyama, Tatsuaki Watanabe, Yui Watanabe, Hirotsugu Notsuda, Takaya Suzuki, Hisashi Oishi and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Surgery today, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Takashi HiramaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan. takashi.hirama.b5@tohoku.ac.jp.ORCID http://orcid.org/0000-0002-9390-5057
Miki AkibaDivision of Organ Transplantation, Tohoku University Hospital, 1-1 Seiryomachi, Sendai, Miyagi, 980-8574, Japan.
Masahiro UiDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Saori ShibataDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Fumiko TomiyamaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Tatsuaki WatanabeDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Yui WatanabeDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Hirotsugu NotsudaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Takaya SuzukiDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Hisashi OishiDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Hiromichi NiikawaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Masafumi NodaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Yoshinori OkadaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Sendai, Miyagi, 980-8575, Japan.
Tohoku University · JPTohoku Institute of Technology · JPTohoku University Hospital · JP

Funding

Institute of Development, Aging and Cancer, Tohoku University Cooperative Research Project Program 2022Japan Society for the Promotion of Science 20K08509Takeda Science Foundation Visionary Research 2021Tokyo-Hokenkai Byotai-Seiri Laboratory Clinical Research Grant 2022
6 · The paper itself

Abstract

purposesDelayed chest closure (DCC) is a widely accepted procedure in the context of lung transplantation (LTx); yet there are few reports detailing its long-term survival and clinical outcomes.

methodsWe reviewed the medical records of recipients who underwent deceased-donor lung transplantation (LTx) at Tohoku University Hospital. Long-term survival, including overall survival, freedom from chronic lung allograft dysfunction (CLAD), and CLAD-free survival and the clinical outcomes of graft function and physical performance and constitution were reviewed in recipients with DCC.

resultsBetween 2009 and 2022, 116 patients underwent LTx, 33 of whom (28.4%) required DCC. The intra-and post-operative courses of the recipients who required DCC were more complicated than those of the recipients who underwent primary chest closure (PCC), with frequent volume reduction surgery and longer periods of invasive mechanical ventilation. Pulmonary vascular disease was considered a risk factor for these complications and DCC. Nonetheless, long-term survival and graft functions were comparable between the DCC and PCC groups. The physical performance and constitution of recipients who required DCC continued to improve, and by 2 years after transplantation, exhibited almost no difference from those who underwent PCC.

conclusionsIn view of the profoundly complicated intra- and post-operative courses, DCC should be performed cautiously and only when clinically indicated, despite which it can result in equivalent long-term survival and acceptable outcomes to PCC.

Indexed as

Lung TransplantationAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSurvival RateThoracic Surgical ProceduresTime FactorsTreatment OutcomeChronic lung allograft dysfunctionDelayed chest closureLung transplantOutcomePhysical performanceSurvival

Identifiers

PMID38546861
PMCPMC11413204
OpenAlexW4393277284

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.