ArticleEuropean radiology2024
Efficacy of microwave ablation in the treatment of large benign thyroid nodules: a multi-center study.
Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 11 citations in OpenAlex.
- The efficacy and safety of microwave ablation in benign large thyroid nodules (≥4 cm).European thyroid journal · 2026Article
- Early volume reduction slope as a novel predictor of long-term outcomes following microwave ablation of benign thyroid nodules: a machine learning-enhanced prediction model.Journal of ultrasound · 2026Article
- Patient-Reported Symptom Relief from Percutaneous Benign Thyroid Nodule Radiofrequency Ablation in Routine Clinical Care.AJNR. American journal of neuroradiology · 2026Article
- Efficacy and safety of ultrasound-guided radiofrequency ablation versus laparoscopic cholecystectomy in gallbladder polyps: a bicentric study.Scientific reports · 2026Article
- Evaluating microwave ablation for treating large benign thyroid nodules.Gland surgery · 2026Article
- Development and validation of a multi-parametric energy density optimization algorithm for microwave ablation of benign thyroid nodules: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Transarterial embolization outperforms radiofrequency ablation for thyroid goiters exceeding 100 mL: a study on efficacy and safety.European radiology · 2026Article
- Efficacy and safety of ultrasound-guided microwave "Near-Total Ablation" for refractory hyperthyroidism: a retrospective study.Frontiers in endocrinology · 2026Article
- Clinical outcomes and functional preservation of microwave ablation versus surgical resection for benign thyroid nodules: a propensity score-matched retrospective cohort study.Frontiers in endocrinology · 2026Article
- Biological Mechanisms of Microwave Ablation in Thyroid Tumors and Its Induced Immunomodulatory Effects.Cancer management and research · 2026Review
- Recurrence after ablation of Bethesda IV thyroid nodule: report of two cases.Gland surgery · 2025Article
- Efficacy and safety of ultrasound-guided percutaneous thermal ablation for abdominal wall metastases: a retrospective study.BMC cancer · 2025Article
- Efficacy and Safety of Thermal Ablation for Solitary Low-Risk T2N0M0 Papillary Thyroid Carcinoma.Korean journal of radiology · 2024Article
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the efficacy, safety, and improvement of symptoms by ultrasound-guided microwave ablation (MWA) for patients with large benign thyroid nodules (BTNs).
methodsEighty-seven patients with 87 BTNs (≥ 4 cm) treated with MWA between April 2015 and March 2021 were enrolled in this retrospective multicenter study, with clinical and ultrasound examinations performed at the 1st, 3rd, 6th, and 12th months. A multivariable linear mixed effects model was employed to explore the alterations in volume and volume reduction ratio (VRR), as well as the potential factors associated with VRR.
resultsThe mean age of the 87 patients was 45.69 ± 14.21 years (range 18-76 years), and the ratio of men to women was 1:4.8. The mean volumes were much decreased at the 12th month after ablation compared to the initial volumes (p < .001). The mean VRR was 76.09% at the 12th month. The technique efficacy (VRR > 50%) was 90.80% at the 12th month. A multivariate analysis revealed that VRR was related to the initial volume (p = .015), annular flow (p = .010), and nodule composition (p = .024). The mean symptomatic score decreased from 4.40 ± 0.28 to 0.26 ± 0.06 at the 12th month (p < .001). At the same time, the mean cosmetic score decreased from 3.22 ± 0.10 to 1.31 ± 0.08 (p < .001).
conclusionMWA could serve as a safe and effective therapy for large BTNs, significantly reducing the volume of BTNs and significantly improving compressive symptoms and appearance problems. CLINICAL RELEVANCE STATEMENT: Microwave ablation could serve as a safe and effective therapy for large benign thyroid nodules, leading to significant volume reduction and satisfied symptom and cosmetic alleviation period. KEY POINTS: • This multicenter study investigated the feasibility and safety of microwave ablation for large benign thyroid nodules. • After ablation, the nodule volume was significantly reduced, and patients' symptoms and appearance problems were significantly improved. • Microwave ablation is feasible for large benign thyroid nodules and has been a supplement treatment.
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