Evidence map›Paper›PMID 38546692›Full record

ArticleHaematologica2024

Cladribine plus cytarabine plus venetoclax in acute myeloid leukemia relapsed or refractory to venetoclax plus hypomethylating agent.

Nickolas Steinauer, Kristen McCullough, Aref Al-Kali, Hassan B Alkhateeb, Kebede H Begna, Abhishek A Mangaonkar, Antoine N Saliba, Mehrdad Torghabeh, Mark R Litzow, William J Hogan and 9 more

Registry-linked trialAbstract readLetter
In one paragraph

Article in Haematologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07423104 (A Phase II Study of Cladribine, Low Dose Cytarabine, and Venetoclax in Treatment of Relapsed/Refractory and Secondary Acute Myeloid Leukemia), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07423104 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Phase II Study of Cladribine, Low Dose Cytarabine, and Venetoclax in Treatment of Relapsed/Refractory and Secondary Acute Myeloid Leukemia

TypeinterventionalSponsorUniversity of RochesterRan2026 to 2030Enrolled24ConditionsAcute Myeloid Leukemia (AML)ArmsCAV
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nickolas SteinauerDivision of Hematology, Mayo Clinic, Rochester, MN.
Kristen McCulloughDivision of Hematology, Mayo Clinic, Rochester, MN.
Aref Al-KaliDivision of Hematology, Mayo Clinic, Rochester, MN.
Hassan B AlkhateebDivision of Hematology, Mayo Clinic, Rochester, MN.
Kebede H BegnaDivision of Hematology, Mayo Clinic, Rochester, MN.
Abhishek A MangaonkarDivision of Hematology, Mayo Clinic, Rochester, MN.
Antoine N SalibaDivision of Hematology, Mayo Clinic, Rochester, MN.
Mehrdad TorghabehDivision of Hematology, Mayo Clinic, Rochester, MN.
Mark R LitzowDivision of Hematology, Mayo Clinic, Rochester, MN.
William J HoganDivision of Hematology, Mayo Clinic, Rochester, MN.
Mithun ShahDivision of Hematology, Mayo Clinic, Rochester, MN.
Mrinal M PatnaikDivision of Hematology, Mayo Clinic, Rochester, MN.
Animesh PardananiDivision of Hematology, Mayo Clinic, Rochester, MN.
Talha BadarDivision of Hematology, Mayo Clinic, Jacksonville, FL.
Hemant MurthyDivision of Hematology, Mayo Clinic, Jacksonville, FL.
James ForanDivision of Hematology, Mayo Clinic, Jacksonville, FL.
Cecilia Arana YiDivision of Hematology, Mayo Clinic, Scottsdale, AZ.
Ayalew TefferiDivision of Hematology, Mayo Clinic, Rochester, MN.
Naseema GangatDivision of Hematology, Mayo Clinic, Rochester, MN. gangat.naseema@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBridged Bicyclo Compounds, HeterocyclicCladribineCytarabineLeukemia, Myeloid, AcuteSulfonamidesAdultAgedDrug Resistance, NeoplasmFemaleHumansMaleMiddle AgedRecurrenceTreatment OutcomeBridged Bicyclo Compounds, HeterocyclicCladribineCytarabineSulfonamidesvenetoclax

Identifiers

PMID38546692
PMCPMC11290516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.