Evidence map›Paper›PMID 38546532›Full record

ArticleAlcohol, clinical & experimental research2024

Do sleep and circadian characteristics predict alcohol use in adult drinkers?

Helen J Burgess, Jonathan P Troost, Muneer Rizvydeen, Fumitaka Kikyo, Nema Kebbeh, Michael Tan, Kathryn A Roecklein, Andrea C King, Brant P Hasler

Open access · hybridAbstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Helen J BurgessDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-3816-8194
Jonathan P TroostMichigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, Michigan, USA.
Muneer RizvydeenDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.
Fumitaka KikyoDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.
Nema KebbehDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.
Michael TanDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.
Kathryn A RoeckleinDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Andrea C KingDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-5943-7109
Brant P HaslerDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3123-1106
University of Michigan · USUniversity of Illinois Chicago · USUniversity of Pittsburgh · USUniversity of Chicago · US

Funding

Proximal prospective associations between circadian alignment, reward function and alcohol use in adolescentsR01AA025626 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HASLER, BRANT P. · 2017 to 2021
$2.8M
The Effect of Alcohol on Retinal Photic Signaling to the Human Circadian SystemR01AA023839 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CAO, DINGCAI · 2016 to 2019
$1.6M
NIAAA NIH HHS R01 AA023839NIAAA NIH HHS R01 AA025626NIH HHS R01 AA023839NIH HHS R01AA025626
6 · The paper itself

Abstract

backgroundWhile sleep and circadian rhythms are recognized contributors to the risk for alcohol use and related problems, few studies have examined whether objective sleep and circadian measures can predict future alcohol use in humans, and no such studies have been conducted in adults. This study examined whether any baseline sleep and/or circadian characteristics of otherwise healthy adults predicted their alcohol use over the subsequent 12 months.

methodsParticipants (21-42 years) included 28 light and 50 heavy drinkers. At baseline, a comprehensive range of self-reported and objective sleep/circadian measures was assessed via questionnaires, wrist actigraphy, and measurement of dim light melatonin onset and circadian photoreceptor responsivity. Following this, the number of alcoholic drinks per week and binge drinking episodes per month were assessed quarterly over the subsequent 12 months. Anticipated effects of alcohol (stimulation, sedation, and rewarding aspects) were also assessed quarterly over the 12 months. Analyses included generalized linear mixed-effects models and causal mediation analysis.

resultsAcross the range of measures, only self-reported insomnia symptoms and a longer total sleep time at baseline predicted more drinks per week and binges per month (ps <0.02). There was a trend for the anticipated alcohol effect of wanting more alcohol at the 6-month timepoint to mediate the relationship between insomnia symptoms at baseline and drinks per week at 12 months (p = 0.069).

conclusionsThese results suggest that in otherwise healthy adults, insomnia symptoms, even if subclinical, are a significant predictor of future drinking, and appear to outweigh the influence of circadian factors on future drinking, at least in otherwise healthy adults. Insomnia symptoms may be a modifiable target for reducing the risk of alcohol misuse.

Indexed as

adultsalcohol responsebinge alcohol usecircadian rhythmssleep

Identifiers

PMID38546532
PMCPMC11015972
OpenAlexW4393256879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.