Evidence map›Paper›PMID 38546209›Full record

Trial reportPsycho-oncology2024

Exploring the role of cancer fatalism and engagement with skin cancer genetic information in diverse primary care patients.

Jennifer L Hay, Yelena Wu, Elizabeth Schofield, Kim Kaphingst, Andrew L Sussman, Delores D Guest, Keith Hunley, Yuelin Li, David Buller, Marianne Berwick

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psycho-oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jennifer L HayDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-3492-9331
Yelena WuHuntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Elizabeth SchofieldDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Kim KaphingstCancer Communication Research, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Andrew L SussmanDepartment of Family and Community Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Delores D GuestUniversity of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico, USA.
Keith HunleyDepartment of Anthropology, University of New Mexico, Albuquerque, New Mexico, USA.
Yuelin LiDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
David BullerKlein Buendel, Inc., Golden, Colorado, USA.
Marianne BerwickDepartment of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
University of New Mexico · USMemorial Sloan Kettering Cancer Center · USUniversity of Utah · USKlein Buendel (United States) · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
Personalized Genomic Testing for Melanoma: Maximizing Personal Utility and ReachR01CA181241 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI BERWICK, MARIANNE, HAY, JENNIFER L · 2014 to 2016
$2.1M
NCATS NIH HHS UL1 TR002384NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA118100NCI NIH HHS R01 CA181241NIH HHS NIH R01 CA181241
6 · The paper itself

Abstract

objectiveTo broaden the currently limited reach of genomic innovations, research is needed to understand how psychosocial and cultural factors influence reactions to genetic testing in diverse subgroups. Cancer fatalism is important in cancer prevention and deserves theoretical and empirical attention in the context of genomics and behavior change.

methodsThe current study employed data from a randomized controlled trial (N = 593) offering skin cancer genetic testing (using the melanocortin-1 receptor [MC1R] gene) in primary care in Albuquerque, New Mexico, USA. We examined interrelations of cancer fatalism with demographics, general health beliefs, perceived risk, perceived control, sun protection and skin screening behaviors and cancer worry in the skin cancer context stratified across Hispanic versus non-Hispanic ethnicity, and examined cancer fatalism as a moderator of intervention effects on study primary outcomes, including 3-month sun protection, cancer worry and perceived risk.

resultsCancer fatalism was significantly related to the perception of control over skin cancer risk behaviors (ps ≤ 0.01) and demographics (ethnicity, education, health literacy; ps < 0.05), but not consistently related to general health beliefs or risk perception. Cancer fatalism did not moderate intervention effects on primary outcomes, except those with higher cancer fatalism randomized to intervention had higher levels of 3-month cancer worry (p = 0.019).

conclusionsThese findings will guide future work considering the role of cancer fatalism in use of genomic technologies in the general population. This work anticipates strategies required to address cancer fatalism as translational genomics becomes more commonly available to diverse general population subgroups.

Indexed as

Health Knowledge, Attitudes, PracticeSkin NeoplasmsGenetic TestingHispanic or LatinoHumansPrimary Health Careattitudesbehavioralcancergeneticshealth psychologyoncologyrisk reduction behaviorskin cancersociodemographic factors

Identifiers

PMID38546209
PMCPMC11391671
OpenAlexW4393259915

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.