Evidence map›Paper›PMID 38546034›Full record

ArticleInternational wound journal2024

Risk factors for amputation in diabetic foot ulcers: A retrospective analysis.

Xiaoyu Zhang, Qiwei Li, Xianpei Zhou, Yu Xu, Zizhen Shu, Hongyu Deng

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in International wound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Risk Factors Associated with Amputation for Patients with Diabetic Foot Ulcers: A Retrospective Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaoyu ZhangHand And Foot Surgery Department of Brain Hospital of Hunan Province, The Second People's Hospital of Hunan Province, Changsha, China.
Qiwei LiHand And Foot Surgery Department of Brain Hospital of Hunan Province, The Second People's Hospital of Hunan Province, Changsha, China.
Xianpei ZhouHand And Foot Surgery Department of Brain Hospital of Hunan Province, The Second People's Hospital of Hunan Province, Changsha, China.
Yu XuHand And Foot Surgery Department of Brain Hospital of Hunan Province, The Second People's Hospital of Hunan Province, Changsha, China.
Zizhen ShuHand And Foot Surgery Department of Brain Hospital of Hunan Province, The Second People's Hospital of Hunan Province, Changsha, China.
Hongyu DengDepartment of Clinical Laboratory, Hunan Key Laboratory of Oncotarget Gene, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Second People Hospital of Hunan · CNCentral South University · CN

Funding

Hunan Provincial Natural Science Foundation of China 2023JJ30370Scientific Research Project of Hunan Provincial Health Commission 20233549The China Postdoctoral Scince Foudation 2022M711125the project of Hunan Provincial Department of Education 20C1427The Science and Technology Innovation Program of Hunan Province 2021SK51110
6 · The paper itself

Abstract

Diabetic foot ulcers (DFUs) are chronic, difficult-to-heal wounds with a very high incidence of amputation. For patients with DFUs, prevention of amputation is crucial. However, the risk factors associated with DFU amputation and the extent to which different risk factors increase the risk of amputation are still uncertain. This study intends to provide a clinical basis for early intervention in DFU by retrospectively analysing the risk factors for DFU amputation. A retrospective analysis of 200 patients with DFUs admitted between October 2019 and October 2023 was conducted. Sixty-eight of the 200 underwent amputations. The overall amputation rate was 34%. Multiple logistic regression model showed that neutrophil/lymphocyte ratio (OR = 1.943; 95% CI:1.826-2.139), white blood cell (OR = 1.143; 95% CI:1.034-1.267), C-reactive protein (OR = 1.307; 95% CI:1.113-2.194) and Wagner grading (OR = 2.783; 95% CI: 1.751-4.302) were independent risk factors for amputation, while haemoglobin (OR = 0.742; 95% CI:0.638-0.965) and high density lipoprotein were independent protective factors for amputation (OR = 0.168; 95% CI:0.037-0.716), and further Receiver Operating Characteristic Curve curves showed that they showed high accuracy and were good predictors of amputation of DFUs.

Indexed as

Diabetes MellitusDiabetic FootAmputation, SurgicalHumansRetrospective StudiesRisk FactorsWound Healingamputationdiabetic foot ulcersinflammatory factorsinfluencing factorswound

Identifiers

PMID38546034
PMCPMC10976421
OpenAlexW4393277721

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.