Evidence map›Paper›PMID 38545880›Full record

ArticleGut microbes

Oral pathobiont

Yijie Guo, Sho Kitamoto, Gustavo Caballero-Flores, Yeji Kim, Daisuke Watanabe, Kohei Sugihara, Gabriel Núñez, Christopher J Alteri, Naohiro Inohara, Nobuhiko Kamada

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  11. Host-pathobiont interactions in Crohn's disease.Nature reviews. Gastroenterology & hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Yijie GuoDepartment of Psychiatry and Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Sho KitamotoWPI Immunology Frontier Research Center, Osaka University, Suita, Japan.
Gustavo Caballero-FloresDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Yeji KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Daisuke WatanabeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Kohei SugiharaWPI Immunology Frontier Research Center, Osaka University, Suita, Japan.
Gabriel NúñezDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Christopher J AlteriDepartment of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI, USA.
Naohiro InoharaDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Nobuhiko KamadaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-1980-4178
University of Michigan · USThe University of Osaka · JPUniversity of Michigan–Dearborn · USUniversity of Wisconsin–Madison · US

Funding

University of Michigan Center for Gastrointestinal ResearchP30DK034933 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OWYANG, CHUNG · 1986 to 2021
$22.5M
The role of IL-1ß-inducing pathobionts in the pathogenesis of Crohn’s diseaseR01DK108901 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Nobuhiko Kamada · 2017 to 2026
$3.8M
The link between oral bacteria and gut diseaseR01DK119219 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KAMADA, NOBUHIKO · 2019 to 2022
$1.6M
Deciphering the pathogenesis of an enteric pathogen in neonatal and immunodeficient miceR00AI159620 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI CABALLERO FLORES, GUSTAVO · 2024 to 2025
$498k
Deciphering the pathogenesis of an enteric pathogen in neonatal and immunodeficient miceK99AI159620 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CABALLERO FLORES, GUSTAVO · 2022 to 2023
$185k
NIAID NIH HHS K99 AI159620NIAID NIH HHS R00 AI159620NIDDK NIH HHS P30 DK034933NIDDK NIH HHS R01 DK108901NIDDK NIH HHS R01 DK119219
6 · The paper itself

Abstract

The ectopic gut colonization by orally derived pathobionts has been implicated in the pathogenesis of various gastrointestinal diseases, including inflammatory bowel disease (IBD). For example, gut colonization by orally derived

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesAnimalsHumansInflammationKlebsiellaMiceMouth MucosaChaperon usher piligut microbiotainflammatory bowel diseaseKlebsiellaoral microbiotapathobiontsperiodontitis

Identifiers

PMID38545880
PMCPMC10984132
OpenAlexW4393277559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.