Evidence map›Paper›PMID 38545809›Full record

Observational studyCancer medicine2024

Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study.

Olivier Malard, Matilde Karakachoff, Christophe Ferron, Stéphane Hans, Sébastien Vergez, Renaud Garrel, Philippe Gorphe, Lionel Ramin, Laure Santini, Alexandre Villeneuve and 3 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Temporary tracheotomy in transoral robotic surgery (TORS): from a retrospective single-center analysis to a proposal of a decision-making algorithm.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Olivier MalardDepartment of Otolaryngology Head and Neck Surgery, Nantes University Hospital, Nantes, France.ORCID 0000-0003-1783-5066
Matilde KarakachoffNantes Université, CHU Nantes, Pôle Hospitalo-Universitaire 11: Santé Publique, Clinique des données, INSERM, CIC 1413, Nantes, France.
Christophe FerronDepartment of Otolaryngology Head and Neck Surgery, Nantes University Hospital, Nantes, France.
Stéphane HansDepartment of Otolaryngology-Head and Neck Surgery, Foch Hospital, Suresnes, France.
Sébastien VergezHead and Neck Surgery Department, Cancer Institute Toulouse-Oncopole, Toulouse, France.ORCID 0000-0003-4081-3922
Renaud GarrelDepartment of Head and Neck Surgery, Montpellier Guy De Chauliac University Hospital, Montpellier, France.
Philippe GorpheDepartment of Head and Neck Oncology, Gustave Roussy Institute, University Paris-Saclay, Villejuif, France.ORCID 0000-0001-7604-4964
Lionel RaminDepartment of Head and Neck Surgery, Limoges Dupuytrens University Hospital, Limoges, France.
Laure SantiniENT-Head and Neck Surgery Department, La Conception University Hospital, Aix Marseille University, Marseille, France.
Alexandre VilleneuveHead and Neck Surgery Department, Georges-Pompidou European Hospital, Paris, France.
Audrey Lasne-CardonDepartment of Head and Neck Surgery, François Baclesse Cancer center, Normandie University, Caen, France.
Florent EspitalierDepartment of Otolaryngology Head and Neck Surgery, Nantes University Hospital, Nantes, France.
Audrey HounkpatinDepartment of Otolaryngology Head and Neck Surgery, Nantes University Hospital, Nantes, France.
Centre Hospitalier Universitaire de Nantes · FRAix-Marseille Université · FRHôpital Dupuytren · FRHôpital Européen Georges-Pompidou · FRHôpital Foch · FRHôpital Gui de Chauliac · FRInserm · FRInstitut Gustave Roussy · FRInstitut universitaire du cancer de Toulouse Oncopole · FRNormandie Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy.

methodsA retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020. Survival was assessed with the Kaplan-Meier method. Prognostic factors were evaluated using a chi-squared test, Fisher's test, or Wilcoxon's test.

resultsThe median length of hospital stay was 12.5 days. Bleeding was the most frequent postoperative complication (15.2%, n = 22). Prophylactic vessel ligation did not significantly decrease bleeding. Complications were significantly lower for Tis, T1, and N0 tumors. 91.6% (n = 120) of the patients with a perioperative tracheotomy could be decannulated. Larynx was functional for 65.94% of the patients. The median length of follow-up was 26 months. The 5-year overall and relapse-free survival rates were respectively 59.9% and 43.4%.

conclusionOncological and functional results confirmed the value of TORS as a treatment in previously irradiated area.

Indexed as

Head and Neck NeoplasmsOropharyngeal NeoplasmsRobotic Surgical ProceduresHumansNeoplasm Recurrence, LocalRetrospective StudiesTreatment Outcomehead and neck cancerradiotherapysquamous cell carcinomatransoral robotic surgery

Identifiers

PMID38545809
PMCPMC10974718
OpenAlexW4393265458

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.