Evidence map›Paper›PMID 38545803›Full record

ArticleJournal of extracellular vesicles2024

The small extracellular vesicle-mediated intercellular transformation of CXCR1

Qiaoshi Xu, Aoming Cheng, Bo Li, Xutengyue Tian, Zhengxue Han, Zhien Feng

Open access · goldAbstract read
In one paragraph

Article in Journal of extracellular vesicles, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qiaoshi XuDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Aoming ChengDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Bo LiDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Xutengyue TianDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Zhengxue HanDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Zhien FengDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-1952-6734
Capital Medical University · CN

Funding

Beijing Hospitals Authority Clinical medicine Development of special funding support YGLX202338Beijing Municipal Administration of Hospitals' Youth Programme QML20231507Beijing Nova Program 20230484404Beijing Science and Technology Commission Z221100007422046Beijing Stomatological Hospital, Capital Medical University Young Scientist Program YSP202111National Natural Science Foundation of China 82072984
6 · The paper itself

Abstract

The heterogeneity of tumour cells enables cancers to dynamically adapt to microenvironmental stresses during progression. However, the mechanism underlying the transformation and intercellular communication between heterogeneous tumour cells has remained elusive. Here, we report a "contagion model" that mediates intercellular transformation between heterogeneous tumour cells which facilitates tumour progression. Initially identifying heterogeneous expression of CXCR1, a receptor for interleukin-8, in head and neck squamous cell carcinoma (HNSCC) tumour cells, we found that CXCR1

Indexed as

Dicarboxylic AcidsExtracellular VesiclesFatty AcidsHead and Neck NeoplasmsCell Line, TumorHumansInterleukin-8Squamous Cell Carcinoma of Head and Neck8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acidDicarboxylic AcidsFatty AcidsInterleukin-8ATP‐citrate lyaseC‐X‐C motif chemokine receptor 1head and neck squamous cell carcinomaheterogeneitysmall extracellular vesicles

Identifiers

PMID38545803
PMCPMC10974724
OpenAlexW4393265518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.