Evidence map›Paper›PMID 38545454›Full record

ReviewFrontiers in neurology2023

Overlapping and distinct phenotypic profiles in Alzheimer's disease and late onset epilepsy: a biologically-based approach.

Anli A Liu, William B Barr

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Neuropsychiatric symptoms in Alzheimer's disease: Bridging mechanisms, management, and emerging innovations.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Anli A LiuLangone Medical Center, New York University, New York, NY, United States.
William B BarrDepartment of Neurology, School of Medicine, New York University, New York, NY, United States.
New York University · USNYU Langone Health · US

Funding

Hippocampal-Neocortical Interactions During Naturalistic LearningR01NS127954 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Anli A Liu · 2023 to 2026
$2.5M
Mechanisms of disrupted memory encoding in epilepsy patients - Resubmission - 1K23NS104252 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIU, ANLI A · 2018 to 2022
$1.0M
NINDS NIH HHS K23 NS104252NINDS NIH HHS R01 NS127954
6 · The paper itself

Abstract

Due to shared hippocampal dysfunction, patients with Alzheimer's dementia and late-onset epilepsy (LOE) report memory decline. Multiple studies have described the epidemiological, pathological, neurophysiological, and behavioral overlap between Alzheimer's Disease and LOE, implying a bi-directional relationship. We describe the neurobiological decline occurring at different spatial in AD and LOE patients, which may explain why their phenotypes overlap and differ. We provide suggestions for clinical recognition of dual presentation and novel approaches for behavioral testing that reflect an "inside-out," or biologically-based approach to testing memory. New memory and language assessments could detect-and treat-memory impairment in AD and LOE at an earlier, actionable stage.

Indexed as

Alzheimer’s diseasehippocampusinterictal epileptiform dischargelanguagelate onset epilepsymemorymild cognitive impairmentneuropsychology

Identifiers

PMID38545454
PMCPMC10965692
OpenAlexW4392757854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.