Evidence map›Paper›PMID 38545334›Full record

ArticleJournal of experimental pharmacology2024

Evaluation of Wound Healing Activity of Hydromethanolic Crude Extract and Solvent Fractions of the Root of

Aziza M Essa, Kefyalew A Getahun, Zewdu Birhanu Wubneh

Open access · goldAbstract read
In one paragraph

Article in Journal of experimental pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Aziza M Essa *Department of Pharmacology, College of Medicine and Health Science, Wolkite University, SNNPR, Wolkite, Ethiopia.ORCID 0009-0002-0748-408X
Kefyalew A Getahun *Department of Pharmacology, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.ORCID 0000-0001-7317-2995
Zewdu Birhanu Wubneh *Department of Pharmacology, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.ORCID 0000-0002-8187-6199
University of Gondar · ETWolkite University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The roots of Methods: The dried root powder of Results: In excision wound, 10% and 5% of crude extract ointment provided a significant (P<0.001) percentage of contraction starting from day 4 and day 6 onwards respectively. Moreover, the rate of epithelialization was significantly (P<0.001) improved in 10% crude extract. In burn wound, 10% and 5% crude extract showed significant (P<0.001) wound contraction starting from day 4 and 8 onwards respectively. In both excision and burn wounds, a moderate concentration of fibroblast proliferation and collagen deposition was observed on the 10% crude extract. The 5% and 10% aqueous and ethyl acetate fractions produced a significant (P<0.001) percentage of wound contraction and shortening of epithelialization at different time points compared to simple ointment. Conclusion: The results of this study demonstrated that the 80% methanolic crude extract, aqueous and ethyl acetate fractions of

Indexed as

crude extractsolvent fractionVerbascum sinaiticumwound healing

Identifiers

PMID38545334
PMCPMC10972568
OpenAlexW4393203332

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.