Evidence map›Paper›PMID 38545321›Full record

ArticleHeart rhythm O22024

Characterizing cardiac contractile motion for noninvasive radioablation of ventricular tachycardia.

Bryan Wu, Todd Atwood, Arno J Mundt, Jennifer Karunamuni, Paul Stark, Albert Hsiao, Frederick Han, Jonathan C Hsu, Kurt Hoffmayer, Farshad Raissi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Bryan WuDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Todd AtwoodDivision of Medical Physics and Technology, Department of Radiation Medicine and Applied Sciences, University of California San Diego, San Diego, California.
Arno J MundtDivision of Medical Physics and Technology, Department of Radiation Medicine and Applied Sciences, University of California San Diego, San Diego, California.
Jennifer KarunamuniDepartment of Radiology, Veterans Affairs San Diego Medical Center, San Diego, California.
Paul StarkDepartment of Radiology, Veterans Affairs San Diego Medical Center, San Diego, California.
Albert HsiaoDivision of Cardiothoracic Radiology, University of California San Diego, San Diego, California.
Frederick HanDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Jonathan C HsuDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Kurt HoffmayerDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Farshad RaissiDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Ulrika Birgersdotter-GreenDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Gregory FeldDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
David E KrummenDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
Gordon HoDivision of Cardiology, Department of Medicine, University of California San Diego, San Diego, California.
University of California San Diego · USSan Francisco VA Medical Center · USUniversity of California San Diego Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Respiratory motion management strategies are used to minimize the effects of breathing on the precision of stereotactic ablative radiotherapy for ventricular tachycardia, but the extent of cardiac contractile motion of the human heart has not been systematically explored. Objective: We aim to assess the magnitude of cardiac contractile motion between different directions and locations in the heart. Methods: Patients with intracardiac leads or valves who underwent 4-dimensional cardiac computed tomography (CT) prior to a catheter ablation procedure for atrial or ventricular arrhythmias at 2 medical centers were studied retrospectively. The displacement of transvenous right atrial appendage, right ventricular (RV) implantable cardioverter-defibrillator, coronary sinus lead tips, and prosthetic cardiac devices across the cardiac cycle were measured in orthogonal 3-dimensional views on a maximal-intensity projection CT reconstruction. Results: A total of 31 preablation cardiac 4-dimensional cardiac CT scans were analyzed. The LV lead tip had significantly greater motion compared with the RV lead in the anterior-posterior direction (6.0 ± 2.2 mm vs 3.8 ± 1.7 mm; Conclusion: The degree of cardiac contractile motion varies significantly (1 mm to 15.2 mm) across different locations in the heart. The effect of contractile motion on the precision of radiotherapy should be assessed on a patient-specific basis.

Indexed as

Cardiac computed tomographyCardiac contractile motionIntracardiac fiducialStereotactic radioablationVentricular arrhythmia

Identifiers

PMID38545321
PMCPMC10964375
OpenAlexW4390129237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.