Evidence map›Paper›PMID 38545230›Full record

ArticleHeliyon2024

Neuroprotective effects of dendrobium endophytes metabolites in SH-SY5Y cells via the Nrf2/Keap1 pathway.

Yan Tian Liang, Jia Meng Liu, Lu Qi Qin, Cong Lu, Jing Sun, Qiong Wang, Yong Yang, Bei Fan, Feng Zhong Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Neuroprotective Effects and Mechanisms of Arecoline Against HInternational journal of molecular sciences · 2025
    Article
  3. Metabolites from thePharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yan Tian LiangCollege of Pharmacy, Hunan University of Traditional Chinese Medicine, Hunan, China.
Jia Meng LiuKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Lu Qi QinKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Cong LuKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Jing SunKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Qiong WangKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Yong YangCollege of Pharmacy, Hunan University of Traditional Chinese Medicine, Hunan, China.
Bei FanKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Feng Zhong WangKey Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Beijing, China/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China.
Chinese Academy of Agricultural Sciences · CNHunan University of Traditional Chinese Medicine · CNMinistry of Agriculture and Rural Affairs · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have revealed that endophytes in plants can produce metabolites with activity that is comparable to or identical to the host. Dendrobine has attracted much attention in the field of neurodegenerative diseases by exhibiting anti-oxidative stress and neuroprotective effects. This study aimed to investigate the protective effects and mechanisms of metabolites of dendrobium endophytes

Indexed as

Dendrobium endophytesNeuroprotectionNrf2Oxidative stressSH-SY5Y

Identifiers

PMID38545230
PMCPMC10965829
OpenAlexW4392906509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.